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Wdr12 Gene Detail
Summary
  • Symbol
    Wdr12
  • Name
    WD repeat domain 12
  • Synonyms
    4933402C23Rik, Ytm1, Ytm1p
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927241
    NCBI Gene: 57750
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:60110520-60137659 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 30.45 cM, cytoband C1-C2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    841 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1927241
 protein coding gene Chr1:60108944-60137804 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016073
 protein coding gene Chr1:60120670-60158289 (-)
A/J MGP_AJ_G0016056
 protein coding gene Chr1:57992069-58020518 (-)
AKR/J MGP_AKRJ_G0016012
 protein coding gene Chr1:59638413-59671678 (-)
BALB/cJ MGP_BALBcJ_G0016011
 protein coding gene Chr1:58018961-58052757 (-)
C3H/HeJ MGP_C3HHeJ_G0015843
 protein coding gene Chr1:59874388-59904428 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016464
 protein coding gene Chr1:62442114-62479417 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014185
 protein coding gene Chr1:54199698-54221983 (-)
CAST/EiJ MGP_CASTEiJ_G0015425
 protein coding gene Chr1:59070095-59093457 (-)
CBA/J MGP_CBAJ_G0015815
 protein coding gene Chr1:64412641-64457493 (-)
DBA/2J MGP_DBA2J_G0015916
 protein coding gene Chr1:57416338-57450672 (-)
FVB/NJ MGP_FVBNJ_G0015918
 protein coding gene Chr1:56711354-56740996 (-)
LP/J MGP_LPJ_G0015988
 protein coding gene Chr1:61001200-61030149 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015938
 protein coding gene Chr1:67305545-67336911 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016511
 protein coding gene Chr1:59532947-59564027 (-)
PWK/PhJ MGP_PWKPhJ_G0015212
 protein coding gene Chr1:56770578-56803410 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014992
 protein coding gene Chr1:59069155-59090771 (-)
WSB/EiJ MGP_WSBEiJ_G0015488
 protein coding gene Chr1:59244769-59268892 (-)



Homology
more
  • Human Ortholog
    WDR12, WD repeat domain 12
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WDR12, WD repeat domain 12
  • Synonyms
    YTM1
  • Links
    NCBI Gene ID: 55759
    neXtProt AC: NX_Q9GZL7
    UniProt: Q9GZL7

  • Chr Location
    2q33.2; chr2:202874261-203014798 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    823
  • Tissues
    75
  • cDNA Data
    76
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 57750 NCBI Gene Model | MGI Sequence Detail 27140 C57BL/6J ±  kb
transcript NM_001199060 RefSeq | MGI Sequence Detail 3124 C57BL/6  
polypeptide Q9JJA4 UniProt | EBI | MGI Sequence Detail 423 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 78
    Genomic 1
    cDNA 76
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:1914795
References
more
  • Summaries
    All 47
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 15
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory