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St7 Gene Detail
Summary
  • Symbol
    St7
  • Name
    suppression of tumorigenicity 7
  • Synonyms
    9430001H04Rik, Fam4a2, HELG, RAY1, SEN4, TSG7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927450
    NCBI Gene: 64213
  • Alliance
    gene page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:17693579-17943022 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 8.00 cM, cytoband A2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    6624 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1927450
 protein coding gene Chr6:17692932-17943024 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030472
 protein coding gene Chr6:14952507-15219807 (+)
A/J MGP_AJ_G0030445
 protein coding gene Chr6:14343168-14595152 (+)
AKR/J MGP_AKRJ_G0030372
 protein coding gene Chr6:14838547-15098837 (+)
BALB/cJ MGP_BALBcJ_G0030454
 protein coding gene Chr6:14433143-14693776 (+)
C3H/HeJ MGP_C3HHeJ_G0030168
 protein coding gene Chr6:14709853-14977933 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030909
 protein coding gene Chr6:15414747-15695376 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028120
 protein coding gene Chr6:13304513-13545208 (+)
CAST/EiJ MGP_CASTEiJ_G0029570
 protein coding gene Chr6:14618800-14888885 (+)
CBA/J MGP_CBAJ_G0030146
 protein coding gene Chr6:15918525-16203053 (+)
DBA/2J MGP_DBA2J_G0030290
 protein coding gene Chr6:14276245-14532229 (+)
FVB/NJ MGP_FVBNJ_G0030244
 protein coding gene Chr6:14110875-14360790 (+)
LP/J MGP_LPJ_G0030377
 protein coding gene Chr6:15038050-15318958 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030280
 protein coding gene Chr6:17099083-17363840 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030939
 protein coding gene Chr6:14727018-14989927 (+)
PWK/PhJ MGP_PWKPhJ_G0029284
 protein coding gene Chr6:13927021-14187898 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029120
 protein coding gene Chr6:14607736-14878911 (+)
WSB/EiJ MGP_WSBEiJ_G0029646
 protein coding gene Chr6:14666730-14926865 (+)



Homology
more
  • Human Ortholog
    ST7, suppression of tumorigenicity 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ST7, suppression of tumorigenicity 7
  • Synonyms
    ETS7q, FAM4A, FAM4A1, HELG, RAY1, SEN4, TSG7
  • Links
    NCBI Gene ID: 7982
    neXtProt AC: NX_Q9NRC1
    UniProt: Q9NRC1

  • Chr Location
    7q31.2; chr7:116953238-117230176 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    753
  • Tissues
    14
  • cDNA Data
    32
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 64213 NCBI Gene Model | MGI Sequence Detail 249444 C57BL/6J ±  kb
    transcript NM_022332 RefSeq | MGI Sequence Detail 2286 C57BL/6  
    polypeptide Q99M96 UniProt | EBI | MGI Sequence Detail 577 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 33
      cDNA 32
      Primer pair 1

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:1924509
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 4
      Gene Ontology 1
      Phenotypes 7
    • Earliest
      J:63711 Vincent JB, et al., Identification of a novel gene on chromosome 7q31 that is interrupted by a translocation breakpoint in an autistic individual [see comments]. Am J Hum Genet. 2000 Aug;67(2):510-4
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory