Vsig2 Gene Detail

Summary

• Symbol
  Vsig2
• Name
  V-set and immunoglobulin domain containing 2
• Synonyms
  1190004B15Rik, 2210413P10Rik, CTM, CTX

• Feature Type
  protein coding gene
• IDs
  MGI:1928009
  NCBI Gene: 57276
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr9:37450551-37455501 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 9, 20.78 cM, cytoband B
• Mapping Data
  3 experiments

Strain
Comparison

• SNPs within 2kb
  180 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1928009	protein coding gene	Chr9:37450551-37455501 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0034567	protein coding gene	Chr9:35538091-35543023 (+)
A/J	MGP_AJ_G0034546	protein coding gene	Chr9:34583722-34588773 (+)
AKR/J	MGP_AKRJ_G0034473	protein coding gene	Chr9:35342230-35347180 (+)
BALB/cJ	MGP_BALBcJ_G0034537	protein coding gene	Chr9:34421478-34426408 (+)
C3H/HeJ	MGP_C3HHeJ_G0034250	protein coding gene	Chr9:35775261-35780191 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0035059	protein coding gene	Chr9:36673932-36678874 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0031985	protein coding gene	Chr9:33687508-33692430 (+)
CAST/EiJ	MGP_CASTEiJ_G0033571	protein coding gene	Chr9:35470195-35475106 (+)
CBA/J	MGP_CBAJ_G0034223	protein coding gene	Chr9:37936658-37941576 (+)
DBA/2J	MGP_DBA2J_G0034381	protein coding gene	Chr9:34631158-34636149 (+)
FVB/NJ	MGP_FVBNJ_G0034322	protein coding gene	Chr9:33883158-33888098 (+)
LP/J	MGP_LPJ_G0034466	protein coding gene	Chr9:35714663-35719467 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0034368	protein coding gene	Chr9:39534829-39539767 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0035078	protein coding gene	Chr9:35281065-35285991 (+)
PWK/PhJ	MGP_PWKPhJ_G0033277	protein coding gene	Chr9:34527222-34532211 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0033111	protein coding gene	Chr9:35477531-35482484 (+)
WSB/EiJ	MGP_WSBEiJ_G0033687	protein coding gene	Chr9:35098344-35103278 (+)

Homology

• Human Ortholog
  VSIG2, V-set and immunoglobulin domain containing 2

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  VSIG2, V-set and immunoglobulin domain containing 2
  
• Synonyms
  2210413P10Rik, CTH, CTXL
• Links
  HGNC:17149

  NCBI Gene ID: 23584

  neXtProt AC: NX_Q96IQ7

  UniProt: Q96IQ7

  
  
• Chr Location
  11q24.2; chr11:124747474-124752255 (-)  GRCh38

---

• MGI Vertebrate Homology
  Vsig2 stringent orthology
  1 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: VSIG2
• Gene Tree
  Vsig2
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  7 phenotype references
  

• All Mutations and Alleles
  7
• Gene trapped
  2
• Targeted
  5
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  16 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  707
• Tissues
  1
• cDNA Data
  8
• Literature Summary
  1

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  43
• RefSeq
  2
• UniProt
  3
• CCDS
  CCDS22980.1

• Ensembl
  ENSMUSG00000001943 (Evidence)
• NCBI Gene
  57276

Representative Sequences			Length	Strain/Species
genomic	57276	NCBI Gene Model | MGI Sequence Detail	4951	C57BL/6J
transcript	NM_020518	RefSeq | MGI Sequence Detail	1170	C57BL/6
polypeptide	Q9Z109	UniProt | EBI | MGI Sequence Detail	328	Not Applicable

Protein
Information

• UniProt
  3 Sequences
• Protein Ontology
  PR:000032670 V-set and immunoglobulin domain-containing protein 2
  (term hierarchy)
• InterPro Domains
  IPR013098 Immunoglobulin I-set
  IPR007110 Immunoglobulin-like domain
  IPR036179 Immunoglobulin-like domain superfamily
  IPR013783 Immunoglobulin-like fold
  IPR003599 Immunoglobulin subtype
  IPR003598 Immunoglobulin subtype 2
  IPR013106 Immunoglobulin V-set domain
  IPR042475 V-set and immunoglobulin domain-containing protein 2
• GlyGen
  Q9Z109 3 sites

Molecular
Reagents

• All nucleic 9

  cDNA 8

  Other 1

  
  

  Microarray probesets 3

Other
Accession IDs

MGI:1916153, MGI:1919617, MGI:2143229

References

• Summaries
  All 29

  Developmental Gene Expression 1

  Gene Ontology 1

  Phenotypes 7
• Earliest
  J:64925 Chretien I, et al., CTX, a Xenopus thymocyte receptor, defines a molecular family conserved throughout vertebrates. Eur J Immunol. 1998 Dec;28(12):4094-104
• Latest
  J:229257 Gu Z, et al., Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550

TSS for Vsig2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr84399	Chr9:37450561-37450575 (+)	17 bp