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Tspan5 Gene Detail
Summary
  • Symbol
    Tspan5
  • Name
    tetraspanin 5
  • Synonyms
    2810455A09Rik, 4930505M03Rik, NET-4, Tm4sf9
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928096
    NCBI Gene: 56224
  • Alliance
    gene page
  • Transcription Start Sites
    20 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:138447609-138610194 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 64.42 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4971 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928096
 protein coding gene Chr3:138447609-138613666 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027934
 protein coding gene Chr3:141812980-141985461 (+)
A/J MGP_AJ_G0027891
 protein coding gene Chr3:136787810-136954593 (+)
AKR/J MGP_AKRJ_G0027857
 protein coding gene Chr3:140422603-140603725 (+)
BALB/cJ MGP_BALBcJ_G0027903
 protein coding gene Chr3:136596907-136765841 (+)
C3H/HeJ MGP_C3HHeJ_G0027633
 protein coding gene Chr3:140762429-140931982 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028347
 protein coding gene Chr3:146702010-146882690 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025685
 protein coding gene Chr3:132201599-132368180 (+)
CAST/EiJ MGP_CASTEiJ_G0027089
 protein coding gene Chr3:140548923-140723903 (+)
CBA/J MGP_CBAJ_G0027610
 protein coding gene Chr3:151688390-151872826 (+)
DBA/2J MGP_DBA2J_G0027749
 protein coding gene Chr3:135912200-136078843 (+)
FVB/NJ MGP_FVBNJ_G0027716
 protein coding gene Chr3:133370651-133539301 (+)
LP/J MGP_LPJ_G0027859
 protein coding gene Chr3:143208104-143377619 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027748
 protein coding gene Chr3:159783598-159964293 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028405
 protein coding gene Chr3:139977226-140148824 (+)
PWK/PhJ MGP_PWKPhJ_G0026813
 protein coding gene Chr3:135692207-135862218 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026640
 protein coding gene Chr3:138100494-138272424 (+)
WSB/EiJ MGP_WSBEiJ_G0027168
 protein coding gene Chr3:140832159-141004998 (+)



Homology
more
  • Human Ortholog
    TSPAN5, tetraspanin 5
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TSPAN5, tetraspanin 5
  • Synonyms
    NET-4, NET4, TM4SF9, TSPAN-5
  • Links
    NCBI Gene ID: 10098
    neXtProt AC: NX_P62079
    UniProt: P62079

  • Chr Location
    4q23; chr4:98470367-98658611 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1030
  • Tissues
    141
  • cDNA Data
    52
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56224 NCBI Gene Model | MGI Sequence Detail 162586 C57BL/6J ±  kb
transcript NM_019571 RefSeq | MGI Sequence Detail 3100 C57BL/6  
polypeptide P62080 UniProt | EBI | MGI Sequence Detail 268 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 55
    cDNA 54
    Other 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:1920043, MGI:1922322, MGI:2139900
References
more
  • Summaries
    All 47
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 5
    Phenotypes 14
  • Earliest
    J:64920 Todd SC, et al., Sequences and expression of six new members of the tetraspanin/TM4SF family. Biochim Biophys Acta. 1998 Jul 30;1399(1):101-4
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory