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Nmi Gene Detail
Summary
  • Symbol
    Nmi
  • Name
    N-myc (and STAT) interactor
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928368
    NCBI Gene: 64685
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:51838517-51863241 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 29.98 cM, cytoband C1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    838 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928368
 protein coding gene Chr2:51838499-51863506 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025730
 protein coding gene Chr2:51245319-51273397 (-)
A/J MGP_AJ_G0025706
 protein coding gene Chr2:49277829-49303429 (-)
AKR/J MGP_AKRJ_G0025676
 protein coding gene Chr2:50700861-50728866 (-)
BALB/cJ MGP_BALBcJ_G0025701
 protein coding gene Chr2:49372717-49399282 (-)
C3H/HeJ MGP_C3HHeJ_G0025462
 protein coding gene Chr2:50691664-50719204 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026147
 protein coding gene Chr2:52750272-52779482 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023553
 protein coding gene Chr2:47266016-47290934 (-)
CAST/EiJ MGP_CASTEiJ_G0024927
 protein coding gene Chr2:50793828-50824348 (-)
CBA/J MGP_CBAJ_G0025442
 protein coding gene Chr2:54750782-54781228 (-)
DBA/2J MGP_DBA2J_G0025573
 protein coding gene Chr2:48920220-48945026 (-)
FVB/NJ MGP_FVBNJ_G0025535
 protein coding gene Chr2:48614925-48639874 (-)
LP/J MGP_LPJ_G0025661
 protein coding gene Chr2:51134133-51163803 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025566
 protein coding gene Chr2:55806588-55835298 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026205
 protein coding gene Chr2:50590075-50618412 (-)
PWK/PhJ MGP_PWKPhJ_G0024668
 protein coding gene Chr2:48793211-48819139 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024474
 protein coding gene Chr2:50812328-50841031 (-)
WSB/EiJ MGP_WSBEiJ_G0024994
 protein coding gene Chr2:50891014-50919409 (-)



Homology
more
  • Human Ortholog
    NMI, N-myc and STAT interactor
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NMI, N-myc and STAT interactor
  • Links
    NCBI Gene ID: 9111
    neXtProt AC: NX_Q13287
    UniProt: Q13287

  • Chr Location
    2q23.3; chr2:151270470-151289894 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 2 alleles in 2 genetic backgrounds
    2 phenotypes from multigenic genotypes
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Conditional knockout in mammary epithelium alters mammary development and increases the aggressiveness and metastatic potential of induced mammary tumors. Mice homozygous for a different null allele exhibit reduced susceptibility to LPS treatment.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    36
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    804
  • Tissues
    97
  • cDNA Data
    37
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 64685 NCBI Gene Model | MGI Sequence Detail 24725 C57BL/6J ±  kb
    transcript NM_001421887 RefSeq | MGI Sequence Detail 1318 C57BL/6  
    polypeptide O35309 UniProt | EBI | MGI Sequence Detail 314 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 38
      cDNA 37
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 3
      Gene Ontology 7
      Phenotypes 10
    • Earliest
      J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
    • Latest
      J:309551 Jing X, et al., IFP35 family proteins promote neuroinflammation and multiple sclerosis. Proc Natl Acad Sci U S A. 2021 Aug 10;118(32):e2102642118
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory