Ranbp9 MGI Mouse Gene Detail - MGI:1928741

Symbol

Ranbp9
Name

RAN binding protein 9
Synonyms

IBAP-1, RanBPM

Feature Type

protein coding gene
IDs

MGI:1928741
NCBI Gene: 56705
Alliance

gene page
Transcription Start Sites

12 TSS

Sequence Map

Chr13:43556151-43634758 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 13, 21.60 cM, cytoband A5
Mapping Data

1 experiment

SNPs within 2kb

1386 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1928741	protein coding gene	Chr13:43556151-43634949 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0020500	protein coding gene	Chr13:41998508-42079057 (-)
A/J	MGP_AJ_G0020454	protein coding gene	Chr13:40567408-40649008 (-)
AKR/J	MGP_AKRJ_G0020432	protein coding gene	Chr13:41687181-41765158 (-)
BALB/cJ	MGP_BALBcJ_G0020450	protein coding gene	Chr13:40776528-40854957 (-)
C3H/HeJ	MGP_C3HHeJ_G0020249	protein coding gene	Chr13:41549534-41628758 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0020883	protein coding gene	Chr13:43287294-43372002 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018470	protein coding gene	Chr13:38667983-38748201 (-)
CAST/EiJ	MGP_CASTEiJ_G0019764	protein coding gene	Chr13:41388265-41472612 (-)
CBA/J	MGP_CBAJ_G0020210	protein coding gene	Chr13:45127582-45208239 (-)
DBA/2J	MGP_DBA2J_G0020332	protein coding gene	Chr13:40127842-40207341 (-)
FVB/NJ	MGP_FVBNJ_G0020311	protein coding gene	Chr13:39655151-39733540 (-)
LP/J	MGP_LPJ_G0020407	protein coding gene	Chr13:42239576-42321003 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020340	protein coding gene	Chr13:45036306-45120526 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0020926	protein coding gene	Chr13:41352174-41431057 (-)
PWK/PhJ	MGP_PWKPhJ_G0019519	protein coding gene	Chr13:40242807-40321656 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0019349	protein coding gene	Chr13:39976763-40060324 (-)
WSB/EiJ	MGP_WSBEiJ_G0019826	protein coding gene	Chr13:41661048-41742713 (-)

Human Ortholog

RANBP9, RAN binding protein 9

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

RANBP9, RAN binding protein 9
Synonyms

BPM90, BPM-L, RanBP7, RANBPM
Links

HGNC:13727

NCBI Gene ID: 10048

neXtProt AC: NX_Q96S59

UniProt: Q96S59
Chr Location

6p23; chr6:13621498-13711835 (-) GRCh38

MGI Vertebrate Homology

Ranbp9 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: RANBP9
Gene Tree

Ranbp9

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Phenotype Summary

39 phenotypes from 3 alleles in 4 genetic backgrounds
18 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

15
Chemically induced (other)

1
Endonuclease-mediated

1
Gene trapped

5
Targeted

8
Genomic Mutations

1 involving Ranbp9
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

41 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Mice homozygous for a null mutation display partial neonatal lethality. Survivors display infertility with impaired spermatogenesis and oogenesis, azoospermia and premature ovarian failure.

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All GO Annotations

25
GO References

12

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

710
Tissues

4
cDNA Data

6
Literature Summary

2

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase ranbp9

ZFIN ranbp9

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All Sequences

52
RefSeq

5
UniProt

6
CCDS

CCDS49252.1

Ensembl

ENSMUSG00000038546 (Evidence)
NCBI Gene

56705

			Length	Strain/Species	Flank
genomic	ENSMUSG00000038546	Ensembl Gene Model \| MGI Sequence Detail	78608	C57BL/6J	± kb
transcript	ENSMUST00000144326	Ensembl \| MGI Sequence Detail	3371	Not Applicable
polypeptide	ENSMUSP00000130636	Ensembl \| MGI Sequence Detail	710	Not Applicable

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UniProt

6 Sequences
Protein Ontology

PR:000013716 Ran-binding protein 9

(term hierarchy)
InterPro Domains

IPR001870 B30.2/SPRY domain

IPR043136 B30.2/SPRY domain superfamily

IPR013320 Concanavalin A-like lectin/glucanase domain superfamily

IPR013144 CRA domain

IPR024964 CTLH/CRA C-terminal to LisH motif domain

IPR006595 CTLH, C-terminal LisH motif

IPR006594 LIS1 homology motif

IPR035782 Ran binding protein 9/10, SPRY domain

IPR003877 SPRY domain

IPR050618 Ubiquitination and Signaling Pathway Regulator

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All nucleic 7

cDNA 6

Primer pair 1

Microarray probesets 5

Summaries

All 55

Developmental Gene Expression 2

Gene Ontology 12

Phenotypes 18
Earliest

J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
Latest

J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

TSS for Ranbp9:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr122267	Chr13:43634931-43634991 (-)	-203 bp
Tssr122266	Chr13:43634697-43634801 (-)	9 bp
Tssr122265	Chr13:43634649-43634667 (-)	100 bp
Tssr122264	Chr13:43634577-43634584 (-)	177 bp
Tssr122263	Chr13:43634557-43634571 (-)	194 bp
Tssr122262	Chr13:43634532-43634543 (-)	220 bp
Tssr122261	Chr13:43634520-43634525 (-)	235 bp
Tssr122260	Chr13:43634497-43634514 (-)	252 bp
Tssr122259	Chr13:43634449-43634481 (-)	293 bp
Tssr122258	Chr13:43632368-43632383 (-)	2,382 bp
Tssr122257	Chr13:43588688-43588689 (-)	46,069 bp
Tssr122256	Chr13:43576900-43576908 (-)	57,854 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24