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Acot9 Gene Detail
Summary
  • Symbol
    Acot9
  • Name
    acyl-CoA thioesterase 9
  • Synonyms
    0610041P13Rik, Acate2, MT-ACT48, p48, U8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928939
    NCBI Gene: 56360
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:154045439-154080650 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 72.38 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    834 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928939
 protein coding gene ChrX:154045439-154080650 (+)
129S1/SvImJ MGP_129S1SvImJ_G0036212
 protein coding gene ChrX:153155143-153192919 (+)
A/J MGP_AJ_G0036182
 protein coding gene ChrX:152423388-152465185 (+)
AKR/J MGP_AKRJ_G0036110
 protein coding gene ChrX:157245214-157284941 (+)
BALB/cJ MGP_BALBcJ_G0036175
 protein coding gene ChrX:150538188-150574473 (+)
C3H/HeJ MGP_C3HHeJ_G0035881
 protein coding gene ChrX:153478488-153514996 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036697
 protein coding gene ChrX:157615636-157651851 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033517
 protein coding gene ChrX:144002059-144041530 (+)
CAST/EiJ MGP_CASTEiJ_G0035169
 protein coding gene ChrX:132646538-132685238 (+)
CBA/J MGP_CBAJ_G0035856
 protein coding gene ChrX:162105256-162142235 (+)
DBA/2J MGP_DBA2J_G0036022
 protein coding gene ChrX:151427499-151467846 (+)
FVB/NJ MGP_FVBNJ_G0035952
 protein coding gene ChrX:150546034-150582162 (+)
LP/J MGP_LPJ_G0036107
 protein coding gene ChrX:154247942-154285911 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035985
 protein coding gene ChrX:170456209-170498119 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036738
 protein coding gene ChrX:152719443-152759850 (+)
PWK/PhJ MGP_PWKPhJ_G0034867
 protein coding gene ChrX:129630690-129670773 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034688
 protein coding gene ChrX:133094168-133134756 (+)
WSB/EiJ MGP_WSBEiJ_G0035304
 protein coding gene ChrX:150723516-150761298 (+)



Homology
more
  • Human Ortholog
    ACOT9, acyl-CoA thioesterase 9
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACOT9, acyl-CoA thioesterase 9
  • Synonyms
    ACATE2, CGI-16, MT-ACT48, MTACT48
  • Links
    NCBI Gene ID: 23597
    neXtProt AC: NX_Q9Y305
    UniProt: Q9Y305

  • Chr Location
    Xp22.11; chrX:23701055-23766475 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    723
  • Tissues
    4
  • cDNA Data
    62
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56360 NCBI Gene Model | MGI Sequence Detail 35212 C57BL/6J ±  kb
transcript NM_001313718 RefSeq | MGI Sequence Detail 1826 C57BL/6  
polypeptide Q9R0X4 UniProt | EBI | MGI Sequence Detail 439 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • EC
    3.1.2.-, 3.1.2.2
  • InterPro Domains
    IPR033120 Hotdog acyl-CoA thioesterase (ACOT)-type domain
    IPR029069 HotDog domain superfamily
  • GlyGen
    Q9R0X4 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 63
    cDNA 63

    Microarray probesets 3
Other
Accession IDs
less
MGI:1914100, MGI:2148044
References
more
  • Summaries
    All 36
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:66335 Poupon V, et al., Molecular cloning and characterization of MT-ACT48, a novel mitochondrial acyl-CoA thioesterase. J Biol Chem. 1999 Jul 2;274(27):19188-94
  • Latest
    J:349093 Dearden L, et al., Maternal obesity increases hypothalamic miR-505-5p expression in mouse offspring leading to altered fatty acid sensing and increased intake of high-fat food. PLoS Biol. 2024 Jun;22(6):e3002641
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory