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Rbm14 Gene Detail
Summary
  • Symbol
    Rbm14
  • Name
    RNA binding motif protein 14
  • Synonyms
    1300007E16Rik, p16, PSP2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929092
    NCBI Gene: 56275
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr19:4850597-4861662 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 4.11 cM, cytoband A
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    268 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929092
 protein coding gene Chr19:4850594-4861662 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024674
 protein coding gene Chr19:1697114-1708821 (-)
A/J MGP_AJ_G0024640
 protein coding gene Chr19:1618436-1629475 (-)
AKR/J MGP_AKRJ_G0024613
 protein coding gene Chr19:1661566-1672629 (-)
BALB/cJ MGP_BALBcJ_G0024640
 protein coding gene Chr19:1613865-1624909 (-)
C3H/HeJ MGP_C3HHeJ_G0024408
 protein coding gene Chr19:1665895-1676953 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025087
 protein coding gene Chr19:1751361-1762416 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022517
 protein coding gene Chr19:1547546-1559307 (-)
CAST/EiJ MGP_CASTEiJ_G0023880
 protein coding gene Chr19:1684914-1696562 (-)
CBA/J MGP_CBAJ_G0024379
 protein coding gene Chr19:1823012-1836919 (-)
DBA/2J MGP_DBA2J_G0024507
 protein coding gene Chr19:1585393-1596566 (-)
FVB/NJ MGP_FVBNJ_G0024474
 protein coding gene Chr19:1606518-1618668 (-)
LP/J MGP_LPJ_G0024593
 protein coding gene Chr19:1704113-1716144 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024504
 protein coding gene Chr19:1729188-1741615 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025135
 protein coding gene Chr19:1657596-1668643 (-)
PWK/PhJ MGP_PWKPhJ_G0023626
 protein coding gene Chr19:1634059-1645949 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023431
 protein coding gene Chr19:1645922-1657305 (-)
WSB/EiJ MGP_WSBEiJ_G0023942
 protein coding gene Chr19:1655676-1667100 (-)



Homology
more
  • Human Ortholog
    RBM14, RNA binding motif protein 14
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RBM14, RNA binding motif protein 14
  • Synonyms
    COAA, PSP2, SIP, SYTIP1, TMEM137
  • Links
    NCBI Gene ID: 10432
    neXtProt AC: NX_Q96PK6
    UniProt: Q96PK6

  • Chr Location
    11q13.2; chr11:66616626-66629934 (+)  GRCh38
  • Human Ortholog
    RBM14-RBM4, RBM14-RBM4 readthrough
  • Synonyms
    COAZ, PSP2, RBM14, SIP
  • Links
    NCBI Gene ID: 100526737
    neXtProt AC: NX_Q96PK6

  • Chr Location
    11q13.2; chr11:66616626-66646469 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 2 alleles in 2 genetic backgrounds
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit embryonic lethality with impaired gastrulation, reduced cell density in the epiblast and mesoderm, and absent allantois, chorion, amnion, and primitive streak.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    738
  • Tissues
    27
  • cDNA Data
    109
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000006456 Ensembl Gene Model | MGI Sequence Detail 11066 C57BL/6J ±  kb
    transcript ENSMUST00000006625 Ensembl | MGI Sequence Detail 3165 Not Applicable  
    polypeptide ENSMUSP00000006625 Ensembl | MGI Sequence Detail 669 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 110
      cDNA 109
      Primer pair 1

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1919021
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 7
      Gene Ontology 8
      Phenotypes 7
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory