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Ap3m1 Gene Detail
Summary
  • Symbol
    Ap3m1
  • Name
    adaptor-related protein complex 3, mu 1 subunit
  • Synonyms
    1200013D09Rik, C78982
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929212
    NCBI Gene: 55946
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:21083810-21102603 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 11.58 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    479 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929212
 protein coding gene Chr14:21081510-21102603 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021050
 protein coding gene Chr14:13831880-13852921 (-)
A/J MGP_AJ_G0020999
 protein coding gene Chr14:13489420-13510472 (-)
AKR/J MGP_AKRJ_G0020976
 protein coding gene Chr14:14023756-14044811 (-)
BALB/cJ MGP_BALBcJ_G0021002
 protein coding gene Chr14:13592715-13613767 (-)
C3H/HeJ MGP_C3HHeJ_G0020786
 protein coding gene Chr14:13963399-13984454 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021435
 protein coding gene Chr14:14311304-14332852 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019003
 protein coding gene Chr14:13796778-13818240 (-)
CAST/EiJ MGP_CASTEiJ_G0020310
 protein coding gene Chr14:13744655-13769315 (-)
CBA/J MGP_CBAJ_G0020752
 protein coding gene Chr14:15046649-15067711 (-)
DBA/2J MGP_DBA2J_G0020875
 protein coding gene Chr14:13315303-13336355 (-)
FVB/NJ MGP_FVBNJ_G0020858
 protein coding gene Chr14:13204407-13225457 (-)
LP/J MGP_LPJ_G0020951
 protein coding gene Chr14:14045668-14066729 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020884
 protein coding gene Chr14:14810526-14831616 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021468
 protein coding gene Chr14:13814630-13835687 (-)
PWK/PhJ MGP_PWKPhJ_G0020059
 protein coding gene Chr14:12891275-12914162 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019881
 protein coding gene Chr14:13608906-13629950 (-)
WSB/EiJ MGP_WSBEiJ_G0020366
 protein coding gene Chr14:13799971-13821123 (-)



Homology
more
  • Human Ortholog
    AP3M1, adaptor related protein complex 3 subunit mu 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AP3M1, adaptor related protein complex 3 subunit mu 1
  • Links
    NCBI Gene ID: 26985
    neXtProt AC: NX_Q9Y2T2
    UniProt: Q9Y2T2

  • Chr Location
    10q22.2; chr10:74120255-74150842 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    136
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 55946 NCBI Gene Model | MGI Sequence Detail 18794 C57BL/6J ±  kb
transcript NM_018829 RefSeq | MGI Sequence Detail 4424 ZRU/MplStud  
polypeptide Q9JKC8 UniProt | EBI | MGI Sequence Detail 418 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 136
    cDNA 136

    Microarray probesets 7
Other
Accession IDs
less
MGI:1353590, MGI:1918977, MGI:2145884
References
more
  • Summaries
    All 39
    Gene Ontology 11
    Phenotypes 6
  • Earliest
    J:20036 Simpson F, et al., Characterization of the adaptor-related protein complex, AP-3. J Cell Biol. 1997 May 19;137(4):835-45
  • Latest
    J:239017 Steinmetz CC, et al., Upregulation of mu3A Drives Homeostatic Plasticity by Rerouting AMPAR into the Recycling Endosomal Pathway. Cell Rep. 2016 Sep 06;16(10):2711-22
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory