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Slc37a2 Gene Detail
Summary
  • Symbol
    Slc37a2
  • Name
    solute carrier family 37 (glycerol-3-phosphate transporter), member 2
  • Synonyms
    ci2, cI-2, G3PP, Slc37a1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929693
    NCBI Gene: 56857
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:37140445-37166709 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 20.74 cM, cytoband B
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    876 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929693
 protein coding gene Chr9:37138881-37167034 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034560
 protein coding gene Chr9:35193149-35221237 (-)
A/J MGP_AJ_G0034539
 protein coding gene Chr9:34267816-34295154 (-)
AKR/J MGP_AKRJ_G0034466
 protein coding gene Chr9:35031054-35057198 (-)
BALB/cJ MGP_BALBcJ_G0034530
 protein coding gene Chr9:34104183-34130641 (-)
C3H/HeJ MGP_C3HHeJ_G0034243
 protein coding gene Chr9:35464227-35490524 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035052
 protein coding gene Chr9:36332059-36360192 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031978
 protein coding gene Chr9:33385739-33412113 (-)
CAST/EiJ MGP_CASTEiJ_G0033564
 protein coding gene Chr9:35151015-35178249 (-)
CBA/J MGP_CBAJ_G0034216
 protein coding gene Chr9:37593541-37622051 (-)
DBA/2J MGP_DBA2J_G0034374
 protein coding gene Chr9:34322892-34349045 (-)
FVB/NJ MGP_FVBNJ_G0034315
 protein coding gene Chr9:33573880-33601363 (-)
LP/J MGP_LPJ_G0034459
 protein coding gene Chr9:35412576-35438116 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034361
 protein coding gene Chr9:39195888-39222018 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035071
 protein coding gene Chr9:34966140-34992986 (-)
PWK/PhJ MGP_PWKPhJ_G0033270
 protein coding gene Chr9:34216900-34243403 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033104
 protein coding gene Chr9:35167819-35197308 (-)
WSB/EiJ MGP_WSBEiJ_G0033680
 protein coding gene Chr9:34764744-34790890 (-)



Homology
more
  • Human Ortholog
    SLC37A2, solute carrier family 37 member 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC37A2, solute carrier family 37 member 2
  • Synonyms
    pp11662, SPX2
  • Links
    NCBI Gene ID: 219855
    neXtProt AC: NX_Q8TED4
    UniProt: Q8TED4

  • Chr Location
    11q24.2; chr11:125063302-125090516 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 2 alleles in 2 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit increased pro-inflammatory cytokine production and accelerated glycolysis and mitochondrial oxidation in macrophages.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    745
  • Tissues
    39
  • cDNA Data
    29
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 56857 NCBI Gene Model | MGI Sequence Detail 26265 C57BL/6J ±  kb
    transcript NM_001145960 RefSeq | MGI Sequence Detail 4111 C57BL/6  
    polypeptide Q9WU81 UniProt | EBI | MGI Sequence Detail 501 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 33
      Genomic 2
      cDNA 29
      Primer pair 2

      Microarray probesets 2
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 3
      Gene Ontology 4
      Phenotypes 11
    • Earliest
      J:66225 Bartoloni L, et al., Cloning and characterization of a putative human glycerol 3-phosphate permease gene (SLC37A1 or G3PP) on 21q22.3: mutation analysis in two candidate phenotypes, DFNB10 and a glycerol kinase deficiency. Genomics. 2000 Dec 1;70(2):190-200
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory