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Bcam Gene Detail
Summary
  • Symbol
    Bcam
  • Name
    basal cell adhesion molecule
  • Synonyms
    1200005K12Rik, B-CAM, Lu
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929940
    NCBI Gene: 57278
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:19490063-19504457 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 9.94 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    501 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929940
 protein coding gene Chr7:19490056-19504941 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031795
 protein coding gene Chr7:17806252-17821970 (-)
A/J MGP_AJ_G0031771
 protein coding gene Chr7:17406341-17420802 (-)
AKR/J MGP_AKRJ_G0031697
 protein coding gene Chr7:17894322-17909544 (-)
BALB/cJ MGP_BALBcJ_G0031776
 protein coding gene Chr7:17613671-17628974 (-)
C3H/HeJ MGP_C3HHeJ_G0031498
 protein coding gene Chr7:18154165-18173224 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032242
 protein coding gene Chr7:18683740-18698219 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029308
 protein coding gene Chr7:19054597-19070084 (-)
CAST/EiJ MGP_CASTEiJ_G0030841
 protein coding gene Chr7:14615439-14631734 (-)
CBA/J MGP_CBAJ_G0031460
 protein coding gene Chr7:19359280-19379046 (-)
DBA/2J MGP_DBA2J_G0031615
 protein coding gene Chr7:17360690-17375136 (-)
FVB/NJ MGP_FVBNJ_G0031567
 protein coding gene Chr7:17232691-17249451 (-)
LP/J MGP_LPJ_G0031698
 protein coding gene Chr7:18114555-18129078 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031603
 protein coding gene Chr7:19174977-19191620 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032270
 protein coding gene Chr7:17507215-17524801 (-)
PWK/PhJ MGP_PWKPhJ_G0030565
 protein coding gene Chr7:14461700-14478228 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030392
 protein coding gene Chr7:12212699-12228695 (-)
WSB/EiJ MGP_WSBEiJ_G0030941
 protein coding gene Chr7:17725789-17741527 (-)



Homology
more
  • Human Ortholog
    BCAM, basal cell adhesion molecule (Lutheran blood group)
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BCAM, basal cell adhesion molecule (Lutheran blood group)
  • Synonyms
    AU, B-CAM, CD239, F8/G253, LU, MSK19
  • Links
    NCBI Gene ID: 4059
    neXtProt AC: NX_P50895
    UniProt: P50895

  • Chr Location
    19q13.32; chr19:44809059-44821421 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    7 phenotypes from multigenic genotypes
    11 phenotype references
A gene trap insertion into an intron of this gene results in no obvious phenotype. Mice homozygous for a null allele exhibit glomeruli abnormalities and increased thickness and disorganization of intestinal smooth muscle.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    740
  • Tissues
    23
  • cDNA Data
    104
  • Literature Summary
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 57278 NCBI Gene Model | MGI Sequence Detail 14395 C57BL/6J ±  kb
transcript NM_020486 RefSeq | MGI Sequence Detail 2407 Not Specified  
polypeptide Q9R069 UniProt | EBI | MGI Sequence Detail 622 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 106
    cDNA 104
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:1918955
References
more
  • Summaries
    All 42
    Developmental Gene Expression 9
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:61456 Rahuel C, et al., Characterization of a mouse liminin receptor gene homologous to the human blood group Lutheran gene. Immunogenetics. 1999 Dec;50(5-6):271-7
  • Latest
    J:327425 Soffer A, et al., Apoptosis and tissue thinning contribute to symmetric cell division in the developing mouse epidermis in a nonautonomous way. PLoS Biol. 2022 Aug;20(8):e3001756
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory