Arl10 MGI Mouse Gene Detail - MGI:1930788 - ADP-ribosylation factor-like 10

Symbol

Arl10
Name

ADP-ribosylation factor-like 10
Synonyms

ARL10, Arl10a, Arm1

Feature Type

protein coding gene
IDs

MGI:1930788
NCBI Gene: 56795
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr13:54722828-54728941 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 13, 28.82 cM
Mapping Data

2 experiments

SNPs within 2kb

219 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1930788	protein coding gene	Chr13:54722828-54730578 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0020571	protein coding gene	Chr13:53979391-53985504 (+)
A/J	MGP_AJ_G0020525	protein coding gene	Chr13:52000021-52006138 (+)
AKR/J	MGP_AKRJ_G0020503	protein coding gene	Chr13:53529536-53534802 (+)
BALB/cJ	MGP_BALBcJ_G0020521	protein coding gene	Chr13:52231682-52237799 (+)
C3H/HeJ	MGP_C3HHeJ_G0020320	protein coding gene	Chr13:53354075-53360192 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0020955	protein coding gene	Chr13:55635896-55642009 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018537	protein coding gene	Chr13:49994864-50001123 (+)
CAST/EiJ	MGP_CASTEiJ_G0019834	protein coding gene	Chr13:53433254-53439359 (+)
CBA/J	MGP_CBAJ_G0020280	protein coding gene	Chr13:57748704-57754938 (+)
DBA/2J	MGP_DBA2J_G0020403	protein coding gene	Chr13:51568470-51574583 (+)
FVB/NJ	MGP_FVBNJ_G0020382	protein coding gene	Chr13:51016295-51022408 (+)
LP/J	MGP_LPJ_G0020479	protein coding gene	Chr13:54256222-54262329 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020411	protein coding gene	Chr13:57244803-57249957 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0020998	protein coding gene	Chr13:53123924-53130037 (+)
PWK/PhJ	MGP_PWKPhJ_G0019590	protein coding gene	Chr13:51554126-51560295 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0019417	protein coding gene	Chr13:52037779-52043850 (+)
WSB/EiJ	MGP_WSBEiJ_G0019896	protein coding gene	Chr13:53461717-53467826 (+)

Human Ortholog

ARL10, ARF like GTPase 10

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ARL10, ARF like GTPase 10
Synonyms

ARL10A
Links

HGNC:22042

NCBI Gene ID: 285598

neXtProt AC: NX_Q8N8L6

UniProt: Q8N8L6
Chr Location

5q35.2

MGI Vertebrate Homology

Arl10 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: ARL10
Gene Tree

Arl10

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References

1 with disease annotations

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Phenotype Summary

3 phenotypes from 1 allele in 1 genetic background
14 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

13
Chemically induced (other)

1
Gene trapped

9
Targeted

3
Genomic Mutations

2 involving Arl10
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

18 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

2
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

722
Tissues

15
cDNA Data

4
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase arl10

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All Sequences

46
RefSeq

6
UniProt

3
CCDS

CCDS26530.1

Ensembl

ENSMUSG00000025870 (Evidence)
NCBI Gene

56795

			Length	Strain/Species	Flank
genomic	ENSMUSG00000025870	Ensembl Gene Model \| MGI Sequence Detail	6114	C57BL/6J	± kb
transcript	ENSMUST00000026988	Ensembl \| MGI Sequence Detail	1046	Not Applicable
polypeptide	ENSMUSP00000026988	Ensembl \| MGI Sequence Detail	243	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000004274 ADP-ribosylation factor-like protein 10

(term hierarchy)
InterPro Domains

IPR042951 ADP-ribosylation factor-like protein 10

IPR027417 P-loop containing nucleoside triphosphate hydrolase

IPR006689 Small GTPase superfamily, ARF/SAR type

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All nucleic 4

cDNA 4

Microarray probesets 4

Summaries

All 38

Developmental Gene Expression 1

Diseases 1

Gene Ontology 2

Phenotypes 14
Earliest

J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Arl10:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr119874	Chr13:54722821-54722830 (+)	-2 bp
Tssr119875	Chr13:54722833-54722906 (+)	42 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24