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Tesc Gene Detail
Summary
  • Symbol
    Tesc
  • Name
    tescalcin
  • Synonyms
    1010001A17Rik, 2410011K10Rik, TE-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1930803
    NCBI Gene: 57816
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:118165808-118199943 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 57.84 cM, cytoband F
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1067 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1930803
 protein coding gene Chr5:118165808-118199943 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029992
 protein coding gene Chr5:121167533-121209024 (+)
A/J MGP_AJ_G0029956
 protein coding gene Chr5:116216772-116254819 (+)
AKR/J MGP_AKRJ_G0029895
 protein coding gene Chr5:119976129-120009440 (+)
BALB/cJ MGP_BALBcJ_G0029967
 protein coding gene Chr5:117644319-117679717 (+)
C3H/HeJ MGP_C3HHeJ_G0029687
 protein coding gene Chr5:120502508-120540323 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030422
 protein coding gene Chr5:125764274-125802907 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027648
 protein coding gene Chr5:110984196-111017156 (+)
CAST/EiJ MGP_CASTEiJ_G0029096
 protein coding gene Chr5:119520961-119560151 (+)
CBA/J MGP_CBAJ_G0029655
 protein coding gene Chr5:130618151-130655847 (+)
DBA/2J MGP_DBA2J_G0029805
 protein coding gene Chr5:116317440-116351766 (+)
FVB/NJ MGP_FVBNJ_G0029761
 protein coding gene Chr5:115209941-115248289 (+)
LP/J MGP_LPJ_G0029893
 protein coding gene Chr5:121659014-121697824 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029792
 protein coding gene Chr5:134796844-134835122 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030463
 protein coding gene Chr5:119520094-119557805 (+)
PWK/PhJ MGP_PWKPhJ_G0028809
 protein coding gene Chr5:115028527-115062985 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028647
 protein coding gene Chr5:117106983-117147139 (+)
WSB/EiJ MGP_WSBEiJ_G0029171
 protein coding gene Chr5:120090249-120130511 (+)



Homology
more
  • Human Ortholog
    TESC, tescalcin
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TESC, tescalcin
  • Synonyms
    CHP3, TSC
  • Links
    NCBI Gene ID: 54997
    neXtProt AC: NX_Q96BS2
    UniProt: Q96BS2

  • Chr Location
    12q24.22; chr12:117038923-117099479 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Mice homozygous for deletions in this gene display normal morphology and numbers of megakaryocytes. Platelet numbers are also normal.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    56
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    936
  • Tissues
    108
  • cDNA Data
    28
  • Literature Summary
    12
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 57816 NCBI Gene Model | MGI Sequence Detail 34136 C57BL/6J ±  kb
transcript NR_151582 RefSeq | MGI Sequence Detail 1036 ZRU/MplStud  
polypeptide Q9JKL5 UniProt | EBI | MGI Sequence Detail 214 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 31
    cDNA 28
    Primer pair 3

    Microarray probesets 4
Other
Accession IDs
less
MGI:1922844, MGI:1923519
References
more
  • Summaries
    All 52
    Developmental Gene Expression 12
    Gene Ontology 11
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:344312 Liu H, et al., Epigenetic repression of Cend1 by lysine-specific demethylase 1 is essential for murine heart development. iScience. 2024 Jan 19;27(1):108722
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory