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Uck2 Gene Detail
Summary
  • Symbol
    Uck2
  • Name
    uridine-cytidine kinase 2
  • Synonyms
    TSA903, Umpk
  • Feature Type
    protein coding gene
  • IDs
    MGI:1931744
    NCBI Gene: 80914
  • Alliance
    gene page
  • Transcription Start Sites
    21 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:167050464-167112657 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 74.61 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2068 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1931744
 protein coding gene Chr1:167050452-167112889 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016711
 protein coding gene Chr1:172772153-172841724 (-)
A/J MGP_AJ_G0016691
 protein coding gene Chr1:165726779-165792408 (-)
AKR/J MGP_AKRJ_G0016657
 protein coding gene Chr1:170740839-170803397 (-)
BALB/cJ MGP_BALBcJ_G0016652
 protein coding gene Chr1:166209314-166272544 (-)
C3H/HeJ MGP_C3HHeJ_G0016476
 protein coding gene Chr1:170967831-171036053 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017113
 protein coding gene Chr1:178564602-178639999 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014822
 protein coding gene Chr1:157575839-157638966 (-)
CAST/EiJ MGP_CASTEiJ_G0016056
 protein coding gene Chr1:170544053-170642223 (-)
CBA/J MGP_CBAJ_G0016451
 protein coding gene Chr1:184896628-184966279 (-)
DBA/2J MGP_DBA2J_G0016557
 protein coding gene Chr1:164573800-164637635 (-)
FVB/NJ MGP_FVBNJ_G0016555
 protein coding gene Chr1:163018516-163086511 (-)
LP/J MGP_LPJ_G0016628
 protein coding gene Chr1:173850422-173919114 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016580
 protein coding gene Chr1:192280936-192352535 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017150
 protein coding gene Chr1:170610443-170673695 (-)
PWK/PhJ MGP_PWKPhJ_G0015842
 protein coding gene Chr1:163752409-163843224 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015628
 protein coding gene Chr1:169347833-169451634 (-)
WSB/EiJ MGP_WSBEiJ_G0016118
 protein coding gene Chr1:170701306-170768094 (-)



Homology
more
  • Human Ortholog
    UCK2, uridine-cytidine kinase 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UCK2, uridine-cytidine kinase 2
  • Synonyms
    TSA903, UK, UMPK
  • Links
    NCBI Gene ID: 7371
    neXtProt AC: NX_Q9BZX2
    UniProt: Q9BZX2

  • Chr Location
    1q24.1; chr1:165827614-165911618 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    16
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    861
  • Tissues
    103
  • cDNA Data
    18
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 80914 NCBI Gene Model | MGI Sequence Detail 62194 C57BL/6J ±  kb
transcript NM_001417920 RefSeq | MGI Sequence Detail 4515 C57BL/6  
polypeptide Q99PM9 UniProt | EBI | MGI Sequence Detail 261 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    cDNA 19

    Microarray probesets 9
Other
Accession IDs
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MGI:2138075, MGI:2138278, MGI:2138414, MGI:2138459
References
more
  • Summaries
    All 44
    Developmental Gene Expression 3
    Gene Ontology 9
    Phenotypes 12
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:347415 Zocher S, et al., Lifelong persistence of nuclear RNAs in the mouse brain. Science. 2024 Apr 5;384(6691):53-59
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory