Prp2 MGI Mouse Gene Detail - MGI:1932491

Symbol

Prp2
Name

proline rich protein 2
Synonyms

MP14

Feature Type

protein coding gene
IDs

MGI:1932491
NCBI Gene: 83380
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr6:132572874-132577665 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 6, 64.03 cM
Mapping Data

1 experiment

SNPs within 2kb

266 from dbSNP Build 142
Strain Annotations

8

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1932491	protein coding gene	Chr6:132572874-132578199 (+)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	MGP_AKRJ_G0031282	protein coding gene	Chr6:135182104-135223411 (+)
BALB/cJ	no annotation
C3H/HeJ	MGP_C3HHeJ_G0031084	protein coding gene	Chr6:135322712-135324292 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0031820	protein coding gene	Chr6:140335568-140337301 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	MGP_FVBNJ_G0031149	protein coding gene	Chr6:129051690-129052272 (+)
LP/J	MGP_LPJ_G0031284	protein coding gene	Chr6:136850691-136856653 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0031190	protein coding gene	Chr6:149534672-149535491 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0031855	protein coding gene	Chr6:135139393-135142121 (+)
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Human Ortholog

PRB1, proline rich protein BstNI subfamily 1

Vertebrate Orthologs

5

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

PRB1, proline rich protein BstNI subfamily 1
Synonyms

PM, PMF, PMS, PRB1L, PRB1M
Links

HGNC:9337

NCBI Gene ID: 5542

neXtProt AC: NX_P04280

UniProt: P04280
Chr Location

12p13.2; chr12:11351821-11355591 (-) GRCh38

Human Ortholog

PRB2, proline rich protein BstNI subfamily 2
Synonyms

cP7, IB-9, PRPPRB1, Ps
Links

HGNC:9338

NCBI Gene ID: 653247

neXtProt AC: NX_P02812

UniProt: P02812
Chr Location

12p13.2

Human Ortholog

PRB3, proline rich protein BstNI subfamily 3
Synonyms

G1, PRG
Links

HGNC:9339

NCBI Gene ID: 5544

UniProt: Q04118
Chr Location

12p13.2; chr12:11265914-11269707 (-) GRCh38

Human Ortholog

PRB4, proline rich protein BstNI subfamily 4
Synonyms

Po
Links

HGNC:9340

NCBI Gene ID: 5545

UniProt: P10163
Chr Location

12p13.2; chr12:11307077-11310436 (-) GRCh38

MGI Vertebrate Homology

Prp2 stringent orthology
4 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: PRB1, PRB2, PRB3, PRB4
Gene Tree

Prp2

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Phenotype Summary

1 phenotype reference

All Mutations and Alleles

1
Targeted

1
Incidental Mutations

APF
Find Mice (IMSR)

11 strains or lines available

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All GO Annotations

1
GO References

1

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

1

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

20
RefSeq

2
UniProt

2
CCDS

CCDS51931.1

Ensembl

ENSMUSG00000058295 (Evidence)
NCBI Gene

83380

			Length	Strain/Species	Flank
genomic	83380	NCBI Gene Model \| MGI Sequence Detail	4792	C57BL/6J	± kb
transcript	NM_031499	RefSeq \| MGI Sequence Detail	986	C57BL/6
polypeptide	P05143	UniProt \| EBI \| MGI Sequence Detail	317	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000013555 proline-rich protein 2

(term hierarchy)
InterPro Domains

IPR026086 Proline-rich protein
GlyGen

P05143 1 site

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All nucleic 6

Genomic 5

cDNA 1

Microarray probesets 4

Summaries

All 19

Gene Ontology 1

Phenotypes 1
Earliest

J:8071 Clements S, et al., Novel multigene families encoding highly repetitive peptide sequences. Sequence analyses of rat and mouse proline-rich protein cDNAs. J Biol Chem. 1985 Nov 5;260(25):13471-7
Latest

J:162220 Magdaleno S, et al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86

TSS for Prp2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr59206	Chr6:132572872-132572876 (+)	0 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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