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Bri3 Gene Detail
Summary
  • Symbol
    Bri3
  • Name
    brain protein I3
  • Synonyms
    I3 protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933174
    NCBI Gene: 55950
  • Alliance
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:144181247-144383567 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 5, 83.19 cM, cytoband G2
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    6329 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1933174
protein coding gene Chr5:144181247-144383567 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030348
protein coding gene Chr5:149575775-149798910 (+)
A/J MGP_AJ_G0030317
protein coding gene Chr5:143155757-143363802 (+)
AKR/J MGP_AKRJ_G0030249
protein coding gene Chr5:147626884-147838499 (+)
BALB/cJ MGP_BALBcJ_G0030334
protein coding gene Chr5:144433605-144634308 (+)
C3H/HeJ MGP_C3HHeJ_G0030045
protein coding gene Chr5:148468840-148680036 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030779
protein coding gene Chr5:155047480-155275105 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027998
protein coding gene Chr5:136940104-137147594 (+)
CAST/EiJ MGP_CASTEiJ_G0029450
protein coding gene Chr5:147986150-148218079 (+)
CBA/J MGP_CBAJ_G0030015
protein coding gene Chr5:161416103-161652688 (+)
DBA/2J MGP_DBA2J_G0030165
protein coding gene Chr5:142903236-143110250 (+)
FVB/NJ MGP_FVBNJ_G0030120
protein coding gene Chr5:142136852-142335717 (+)
LP/J MGP_LPJ_G0030251
protein coding gene Chr5:150192434-150399519 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030151
protein coding gene Chr5:163779714-164022214 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030819
protein coding gene Chr5:147513218-147738883 (+)
PWK/PhJ MGP_PWKPhJ_G0029165
protein coding gene Chr5:142018335-142232108 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029001
protein coding gene Chr5:145249931-145464641 (+)
WSB/EiJ MGP_WSBEiJ_G0029523
protein coding gene Chr5:148308410-148532929 (+)



Homology
more
  • Human Ortholog
    BRI3, brain protein I3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BRI3, brain protein I3
  • Synonyms
    I3
  • Links
    NCBI Gene ID: 25798
    neXtProt AC: NX_O95415
    UniProt: O95415

  • Chr Location
    7q21.3; chr7:98252379-98323430 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic 55950 NCBI Gene Model | MGI Sequence Detail 202321 C57BL/6J ±  kb
    transcript NR_190571 RefSeq | MGI Sequence Detail 1073 C57BL/6  
    polypeptide P28662 UniProt | EBI | MGI Sequence Detail 125 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 49
      cDNA 48
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 30
      Developmental Gene Expression 2
      Gene Ontology 2
      Phenotypes 7
    • Earliest
      J:15086 Kato K, A collection of cDNA clones with specific expression patterns in mouse brain. Eur J Neurosci. 1990;2(8):704-11
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    12/10/2024
    MGI 6.24
    The Jackson Laboratory