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Castor2 Gene Detail
Summary
  • Symbol
    Castor2
  • Name
    cytosolic arginine sensor for mTORC1 subunit 2
  • Synonyms
    Gats, Gatsl2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933384
    NCBI Gene: 80909
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:134128587-134170621 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 74.39 cM, cytoband G1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1359 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1933384
 protein coding gene Chr5:134128550-134173182 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030151
 protein coding gene Chr5:138453508-138503853 (+)
A/J MGP_AJ_G0030119
 protein coding gene Chr5:132587826-132644387 (+)
AKR/J MGP_AKRJ_G0030052
 protein coding gene Chr5:136874274-136923431 (+)
BALB/cJ MGP_BALBcJ_G0030129
 protein coding gene Chr5:133928961-133974351 (+)
C3H/HeJ MGP_C3HHeJ_G0029845
 protein coding gene Chr5:137419559-137471534 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030582
 protein coding gene Chr5:143682144-143731441 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027806
 protein coding gene Chr5:126874368-126918875 (+)
CAST/EiJ MGP_CASTEiJ_G0029254
 protein coding gene Chr5:136860251-136913587 (+)
CBA/J MGP_CBAJ_G0029815
 protein coding gene Chr5:149275222-149326561 (+)
DBA/2J MGP_DBA2J_G0029966
 protein coding gene Chr5:132503893-132548813 (+)
FVB/NJ MGP_FVBNJ_G0029922
 protein coding gene Chr5:131623800-131671817 (+)
LP/J MGP_LPJ_G0030054
 protein coding gene Chr5:138949359-138994877 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029953
 protein coding gene Chr5:152398006-152445222 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030622
 protein coding gene Chr5:136606059-136660592 (+)
PWK/PhJ MGP_PWKPhJ_G0028969
 protein coding gene Chr5:131511628-131559590 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028804
 protein coding gene Chr5:134177520-134226627 (+)
WSB/EiJ MGP_WSBEiJ_G0029328
 protein coding gene Chr5:137343826-137391329 (+)



Homology
more
  • Human Ortholog
    CASTOR2, cytosolic arginine sensor for mTORC1 subunit 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CASTOR2, cytosolic arginine sensor for mTORC1 subunit 2
  • Synonyms
    GATSL1, GATSL2
  • Links
    NCBI Gene ID: 729438
    neXtProt AC: NX_A6NHX0
    UniProt: A6NHX0, Q8N976

  • Chr Location
    7q11.23; chr7:74964705-75031528 (+)  GRCh38
  • Human Ortholog
    CASTOR3P, CASTOR family member 3, pseudogene
  • Synonyms
    CASTOR3, GATS, STAG3OS
  • Links
    NCBI Gene ID: 352954
    neXtProt AC: NX_Q8NAP1
    UniProt: Q8NAP1

  • Chr Location
    7q22.1; chr7:100200653-100272232 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    10
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 80909 NCBI Gene Model | MGI Sequence Detail 42035 C57BL/6J ±  kb
transcript NM_030719 RefSeq | MGI Sequence Detail 4807 C57BL/6  
polypeptide Q8CAB8 UniProt | EBI | MGI Sequence Detail 329 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 8
Other
Accession IDs
less
MGI:2141244, MGI:6156416
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory