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Ptov1 Gene Detail
Summary
  • Symbol
    Ptov1
  • Name
    prostate tumor over expressed gene 1
  • Synonyms
    1110030G05Rik, Gcap3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933946
    NCBI Gene: 84113
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:44512491-44519212 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 28.94 cM, cytoband B2
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    242 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1933946
 protein coding gene Chr7:44512491-44523542 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032183
 protein coding gene Chr7:45071106-45077834 (-)
A/J MGP_AJ_G0032162
 protein coding gene Chr7:44226448-44233176 (-)
AKR/J MGP_AKRJ_G0032098
 protein coding gene Chr7:45443958-45450420 (-)
BALB/cJ MGP_BALBcJ_G0032174
 protein coding gene Chr7:44226192-44233041 (-)
C3H/HeJ MGP_C3HHeJ_G0031890
 protein coding gene Chr7:45945445-45952173 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032666
 protein coding gene Chr7:47336824-47343576 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029680
 protein coding gene Chr7:46796899-46803393 (-)
CAST/EiJ MGP_CASTEiJ_G0031218
 protein coding gene Chr7:37315477-37323037 (-)
CBA/J MGP_CBAJ_G0031854
 protein coding gene Chr7:48888643-48895055 (-)
DBA/2J MGP_DBA2J_G0032012
 protein coding gene Chr7:43897466-43904194 (-)
FVB/NJ MGP_FVBNJ_G0031963
 protein coding gene Chr7:43675054-43681773 (-)
LP/J MGP_LPJ_G0032090
 protein coding gene Chr7:45753546-45760283 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032000
 protein coding gene Chr7:47624796-47631544 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032682
 protein coding gene Chr7:44666783-44673520 (-)
PWK/PhJ MGP_PWKPhJ_G0030941
 protein coding gene Chr7:37261827-37268627 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030778
 protein coding gene Chr7:32667206-32673891 (-)
WSB/EiJ MGP_WSBEiJ_G0031335
 protein coding gene Chr7:45141416-45148144 (-)



Homology
more
  • Human Ortholog
    PTOV1, PTOV1 extended AT-hook containing adaptor protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PTOV1, PTOV1 extended AT-hook containing adaptor protein
  • Synonyms
    ACID2, PTOV-1
  • Links
    NCBI Gene ID: 53635
    neXtProt AC: NX_Q86YD1
    UniProt: Q86YD1

  • Chr Location
    19q13.33; chr19:49850705-49860744 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    729
  • Tissues
    17
  • cDNA Data
    18
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000038502 Ensembl Gene Model | MGI Sequence Detail 6722 C57BL/6J ±  kb
    transcript ENSMUST00000046575 Ensembl | MGI Sequence Detail 1883 Not Applicable  
    polypeptide ENSMUSP00000035281 Ensembl | MGI Sequence Detail 416 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      6 Sequences
    • Protein Ontology
      PR:000013439 prostate tumor-overexpressed gene 1 protein
      (term hierarchy)
    • InterPro Domains
      IPR038196 Mediator complex subunit 25, PTOV domain superfamily
      IPR021394 Mediator complex, subunit Med25, PTOV domain
    Molecular
    Reagents
    less
    • All nucleic 19
      cDNA 19

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-18676, MGI:101852, MGI:1915901, MGI:2142152
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 3
      Gene Ontology 4
      Phenotypes 10
    • Earliest
      J:19885 Kambouris M, et al., Novel cDNA clones obtained by antibody screening of a mouse cerebellar cDNA expression library. Brain Res Mol Brain Res. 1994 Sep;25(3-4):183-91
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    12/10/2024
    MGI 6.24     		The Jackson Laboratory