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Pi15 Gene Detail
Summary
  • Symbol
    Pi15
  • Name
    peptidase inhibitor 15
  • Synonyms
    P24TI, P25TI, SugarCrisp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1934659
    NCBI Gene: 94227
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:17672125-17701163 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 5.32 cM, cytoband A4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1083 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1934659
 protein coding gene Chr1:17672064-17701169 (+)
129S1/SvImJ MGP_129S1SvImJ_G0015862
 protein coding gene Chr1:15149272-15186648 (+)
A/J MGP_AJ_G0015843
 protein coding gene Chr1:14952005-14981051 (+)
AKR/J MGP_AKRJ_G0015802
 protein coding gene Chr1:14954509-14985119 (+)
BALB/cJ MGP_BALBcJ_G0015799
 protein coding gene Chr1:14656689-14686031 (+)
C3H/HeJ MGP_C3HHeJ_G0015633
 protein coding gene Chr1:15009289-15049026 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016253
 protein coding gene Chr1:15837768-15868047 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0013974
 protein coding gene Chr1:13442499-13471979 (+)
CAST/EiJ MGP_CASTEiJ_G0015214
 protein coding gene Chr1:15064326-15094380 (+)
CBA/J MGP_CBAJ_G0015606
 protein coding gene Chr1:16169161-16208394 (+)
DBA/2J MGP_DBA2J_G0015705
 protein coding gene Chr1:14533396-14565019 (+)
FVB/NJ MGP_FVBNJ_G0015710
 protein coding gene Chr1:14301957-14330120 (+)
LP/J MGP_LPJ_G0015777
 protein coding gene Chr1:15348176-15377146 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015729
 protein coding gene Chr1:16849397-16884158 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016300
 protein coding gene Chr1:14944527-14975402 (+)
PWK/PhJ MGP_PWKPhJ_G0014998
 protein coding gene Chr1:14283692-14315092 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014779
 protein coding gene Chr1:15055432-15087094 (+)
WSB/EiJ MGP_WSBEiJ_G0015277
 protein coding gene Chr1:14882733-14913751 (+)



Homology
more
  • Human Ortholog
    PI15, peptidase inhibitor 15
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PI15, peptidase inhibitor 15
  • Synonyms
    CRISP8, P24TI, P25TI
  • Links
    NCBI Gene ID: 51050
    neXtProt AC: NX_O43692
    UniProt: O43692

  • Chr Location
    8q21.13; chr8:74824534-74855029 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    713
  • Tissues
    6
  • cDNA Data
    7
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000067780 Ensembl Gene Model | MGI Sequence Detail 29039 C57BL/6J ±  kb
transcript ENSMUST00000088476 Ensembl | MGI Sequence Detail 6923 Not Applicable  
polypeptide ENSMUSP00000085826 Ensembl | MGI Sequence Detail 269 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:69449 Smith DM, et al., Cloning and expression of a novel cysteine-rich secreted protein family member expressed in thyroid and pancreatic mesoderm within the chicken embryo. Mech Dev. 2001;102(1-2):223-6
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory