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Gprc5d Gene Detail
Summary
  • Symbol
    Gprc5d
  • Name
    G protein-coupled receptor, family C, group 5, member D
  • Feature Type
    protein coding gene
  • IDs
    MGI:1935037
    NCBI Gene: 93746
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:135082989-135095281 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 65.89 cM, cytoband G1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    459 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1935037
 protein coding gene Chr6:135082989-135095281 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031414
 protein coding gene Chr6:139436814-139448786 (-)
A/J MGP_AJ_G0031390
 protein coding gene Chr6:133940516-133952590 (-)
AKR/J MGP_AKRJ_G0031317
 protein coding gene Chr6:138010871-138025352 (-)
BALB/cJ MGP_BALBcJ_G0031396
 protein coding gene Chr6:133761208-133773659 (-)
C3H/HeJ MGP_C3HHeJ_G0031118
 protein coding gene Chr6:138051030-138063031 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031856
 protein coding gene Chr6:143227740-143241083 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028988
 protein coding gene Chr6:133086731-133098680 (-)
CAST/EiJ MGP_CASTEiJ_G0030487
 protein coding gene Chr6:137483245-137505093 (-)
CBA/J MGP_CBAJ_G0031077
 protein coding gene Chr6:148556948-148568949 (-)
DBA/2J MGP_DBA2J_G0031235
 protein coding gene Chr6:132789770-132801747 (-)
FVB/NJ MGP_FVBNJ_G0031185
 protein coding gene Chr6:131706475-131718438 (-)
LP/J MGP_LPJ_G0031319
 protein coding gene Chr6:139525394-139537348 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031225
 protein coding gene Chr6:152587264-152599281 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031889
 protein coding gene Chr6:137757860-137769800 (-)
PWK/PhJ MGP_PWKPhJ_G0030212
 protein coding gene Chr6:131291271-131303742 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030036
 protein coding gene Chr6:135930899-135942788 (-)
WSB/EiJ MGP_WSBEiJ_G0030578
 protein coding gene Chr6:138394181-138407564 (-)



Homology
more
  • Human Ortholog
    GPRC5D, G protein-coupled receptor class C group 5 member D
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GPRC5D, G protein-coupled receptor class C group 5 member D
  • Links
    NCBI Gene ID: 55507
    neXtProt AC: NX_Q9NZD1
    UniProt: Q9NZD1

  • Chr Location
    12p13.1; chr12:12940575-12952170 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    735
  • Tissues
    24
  • cDNA Data
    16
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 93746 NCBI Gene Model | MGI Sequence Detail 12293 C57BL/6J ±  kb
transcript NM_001205396 RefSeq | MGI Sequence Detail 1392 C57BL/6  
polypeptide Q9JIL6 UniProt | EBI | MGI Sequence Detail 344 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    cDNA 16
    Primer pair 2
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 31
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:69085 Brauner-Osborne H, et al., Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D. Biochim Biophys Acta. 2001 Apr 16;1518(3):237-48
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory