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Pcdhgb7 Gene Detail
Summary
  • Symbol
    Pcdhgb7
  • Name
    protocadherin gamma subfamily B, 7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1935199
    NCBI Gene: 93704
  • Member of
    Pcdhg cluster
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:37884672-37974923 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 18, 19.62 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2553 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1935199
protein coding gene Chr18:37884672-37974923 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024348
protein coding gene Chr18:36158529-36259977 (+)
A/J no annotation
AKR/J MGP_AKRJ_G0024284
protein coding gene Chr18:35876830-35972570 (+)
BALB/cJ MGP_BALBcJ_G0024315
protein coding gene Chr18:34985644-35077409 (+)
C3H/HeJ MGP_C3HHeJ_G0024081
protein coding gene Chr18:35947006-36038769 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024757
protein coding gene Chr18:37456946-37559702 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022196
protein coding gene Chr18:34936548-35028291 (+)
CAST/EiJ MGP_CASTEiJ_G0023556
protein coding gene Chr18:35880219-35977834 (+)
CBA/J MGP_CBAJ_G0024051
protein coding gene Chr18:38568913-38667943 (+)
DBA/2J MGP_DBA2J_G0024181
protein coding gene Chr18:34521003-34611340 (+)
FVB/NJ MGP_FVBNJ_G0024147
protein coding gene Chr18:34229666-34321591 (+)
LP/J MGP_LPJ_G0024265
protein coding gene Chr18:36229478-36321813 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024178
protein coding gene Chr18:39832978-39929365 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024806
protein coding gene Chr18:35731919-35837204 (+)
PWK/PhJ MGP_PWKPhJ_G0023300
protein coding gene Chr18:34724519-34819114 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023105
protein coding gene Chr18:35960506-36054330 (+)
WSB/EiJ MGP_WSBEiJ_G0023619
protein coding gene Chr18:35636823-35737854 (+)



Homology
more
  • Human Ortholog
    PCDHGB7, protocadherin gamma subfamily B, 7
  • Vertebrate Orthologs
    12
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PCDHGB7, protocadherin gamma subfamily B, 7
  • Synonyms
    ME6, PCDH-GAMMA-B7
  • Links
    NCBI Gene ID: 56099
    neXtProt AC: NX_Q9Y5F8
    UniProt: Q9Y5F8

  • Chr Location
    5q31.3; chr5:141417645-141512975 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 93704 NCBI Gene Model | MGI Sequence Detail 90252 C57BL/6J ±  kb
transcript NM_033579 RefSeq | MGI Sequence Detail 4691 C57BL/6  
polypeptide NP_291057 RefSeq | MGI Sequence Detail 929 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    Genomic 2
    cDNA 3
    Primer pair 4
References
more
  • Summaries
    All 22
    Developmental Gene Expression 5
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:67989 Wu Q, et al., Comparative dna sequence analysis of mouse and human protocadherin gene clusters. Genome Res. 2001 Mar;11(3):389-404
  • Latest
    J:332241 Kobayashi H, et al., Isoform requirement of clustered protocadherin for preventing neuronal apoptosis and neonatal lethality. iScience. 2023 Jan 20;26(1):105766

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory