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Pcdhgc4 Gene Detail
Summary
  • Symbol
    Pcdhgc4
  • Name
    protocadherin gamma subfamily C, 4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1935203
    NCBI Gene: 93707
  • Member of
    Pcdhg cluster
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:37948132-37974926 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 19.68 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    547 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1935203
 protein coding gene Chr18:37948132-37974926 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024352
 protein coding gene Chr18:36232308-36259977 (+)
A/J MGP_AJ_G0024319
 protein coding gene Chr18:34984401-35011794 (+)
AKR/J MGP_AKRJ_G0024288
 protein coding gene Chr18:35942912-35972570 (+)
BALB/cJ MGP_BALBcJ_G0024319
 protein coding gene Chr18:35050604-35077409 (+)
C3H/HeJ MGP_C3HHeJ_G0024085
 protein coding gene Chr18:36011413-36038769 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024761
 protein coding gene Chr18:37529759-37559702 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022200
 protein coding gene Chr18:35001720-35028291 (+)
CAST/EiJ MGP_CASTEiJ_G0023560
 protein coding gene Chr18:35949782-35977834 (+)
CBA/J MGP_CBAJ_G0024055
 protein coding gene Chr18:38638546-38667943 (+)
DBA/2J MGP_DBA2J_G0024185
 protein coding gene Chr18:34583842-34611340 (+)
FVB/NJ MGP_FVBNJ_G0024151
 protein coding gene Chr18:34294352-34321591 (+)
LP/J MGP_LPJ_G0024269
 protein coding gene Chr18:36293384-36321813 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024182
 protein coding gene Chr18:39899558-39929365 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024810
 protein coding gene Chr18:35804977-35837204 (+)
PWK/PhJ MGP_PWKPhJ_G0023304
 protein coding gene Chr18:34790413-34819114 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023109
 protein coding gene Chr18:36025899-36054330 (+)
WSB/EiJ MGP_WSBEiJ_G0023623
 protein coding gene Chr18:35706881-35737854 (+)



Homology
more
  • Human Ortholog
    PCDHGC4, protocadherin gamma subfamily C, 4
  • Vertebrate Orthologs
    10
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PCDHGC4, protocadherin gamma subfamily C, 4
  • Synonyms
    NEDGS, PCDH-GAMMA-C4
  • Links
    NCBI Gene ID: 56098
    neXtProt AC: NX_Q9Y5F7
    UniProt: Q9Y5F7

  • Chr Location
    5q31.3; chr5:141484997-141512975 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    730
  • Tissues
    12
  • cDNA Data
    7
  • Literature Summary
    10
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 93707 NCBI Gene Model | MGI Sequence Detail 26795 C57BL/6J ±  kb
transcript NM_033582 RefSeq | MGI Sequence Detail 5047 C57BL/6  
polypeptide NP_291060 RefSeq | MGI Sequence Detail 941 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    Genomic 2
    cDNA 8
    Primer pair 4
References
more
  • Summaries
    All 30
    Developmental Gene Expression 10
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:67989 Wu Q, et al., Comparative dna sequence analysis of mouse and human protocadherin gene clusters. Genome Res. 2001 Mar;11(3):389-404
  • Latest
    J:358998 Leon WRM, et al., The clustered gamma protocadherin PcdhgammaC4 isoform regulates cortical interneuron programmed cell death in the mouse cortex. Proc Natl Acad Sci U S A. 2024 Feb 6;121(6):e2313596120
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory