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Pard6g Gene Detail
Summary
  • Symbol
    Pard6g
  • Name
    par-6 family cell polarity regulator gamma
  • Synonyms
    2410049N21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2135606
    NCBI Gene: 93737
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:80090105-80162854 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 53.22 cM, cytoband E3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2159 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2135606
 protein coding gene Chr18:80090045-80162855 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024587
 protein coding gene Chr18:80939483-81020572 (+)
A/J MGP_AJ_G0024554
 protein coding gene Chr18:77394285-77469685 (+)
AKR/J MGP_AKRJ_G0024525
 protein coding gene Chr18:79711713-79787852 (+)
BALB/cJ MGP_BALBcJ_G0024552
 protein coding gene Chr18:77575016-77648878 (+)
C3H/HeJ MGP_C3HHeJ_G0024321
 protein coding gene Chr18:79803649-79879191 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024999
 protein coding gene Chr18:83030730-83108691 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022430
 protein coding gene Chr18:76256990-76328896 (+)
CAST/EiJ MGP_CASTEiJ_G0023794
 protein coding gene Chr18:80127868-80207290 (+)
CBA/J MGP_CBAJ_G0024291
 protein coding gene Chr18:86048651-86131696 (+)
DBA/2J MGP_DBA2J_G0024421
 protein coding gene Chr18:76951324-77025300 (+)
FVB/NJ MGP_FVBNJ_G0024387
 protein coding gene Chr18:76269189-76342763 (+)
LP/J MGP_LPJ_G0024505
 protein coding gene Chr18:80812068-80887241 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024417
 protein coding gene Chr18:87274260-87355130 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025048
 protein coding gene Chr18:79849409-79931536 (+)
PWK/PhJ MGP_PWKPhJ_G0023539
 protein coding gene Chr18:77336369-77412112 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023345
 protein coding gene Chr18:80038546-80113883 (+)
WSB/EiJ MGP_WSBEiJ_G0023857
 protein coding gene Chr18:79811044-79888489 (+)



Homology
more
  • Human Ortholog
    PARD6G, par-6 family cell polarity regulator gamma
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PARD6G, par-6 family cell polarity regulator gamma
  • Synonyms
    PAR-6G, PAR6gamma
  • Links
    NCBI Gene ID: 84552
    neXtProt AC: NX_Q9BYG4
    UniProt: Q9BYG4

  • Chr Location
    18q23; chr18:80157232-80247514 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    831
  • Tissues
    20
  • cDNA Data
    49
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000056214 Ensembl Gene Model | MGI Sequence Detail 72750 C57BL/6J ±  kb
transcript ENSMUST00000070219 Ensembl | MGI Sequence Detail 3147 Not Applicable  
polypeptide ENSMUSP00000069182 Ensembl | MGI Sequence Detail 382 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 50
    cDNA 49
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1914630
References
more
  • Summaries
    All 36
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:69174 Joberty G, et al., The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. Nat Cell Biol. 2000 Aug;2(8):531-9
  • Latest
    J:315122 Passer D, et al., Atypical Protein Kinase C-Dependent Polarized Cell Division Is Required for Myocardial Trabeculation. Cell Rep. 2016 Feb 23;14(7):1662-1672
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory