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Tm2d1 Gene Detail
Summary
  • Symbol
    Tm2d1
  • Name
    TM2 domain containing 1
  • Synonyms
    2310026L18Rik, Bbp
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137022
    NCBI Gene: 94043
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:98243607-98271523 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 45.60 cM, cytoband C6
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1003 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2137022
 protein coding gene Chr4:98243607-98271543 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028471
 protein coding gene Chr4:98514795-98546077 (-)
A/J MGP_AJ_G0028434
 protein coding gene Chr4:95086269-95116300 (-)
AKR/J MGP_AKRJ_G0028381
 protein coding gene Chr4:97392436-97421393 (-)
BALB/cJ MGP_BALBcJ_G0028452
 protein coding gene Chr4:95334930-95363386 (-)
C3H/HeJ MGP_C3HHeJ_G0028165
 protein coding gene Chr4:98191415-98218897 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028891
 protein coding gene Chr4:102285684-102316293 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026183
 protein coding gene Chr4:90479818-90506989 (-)
CAST/EiJ MGP_CASTEiJ_G0027605
 protein coding gene Chr4:95988782-96025859 (-)
CBA/J MGP_CBAJ_G0028134
 protein coding gene Chr4:105366994-105397496 (-)
DBA/2J MGP_DBA2J_G0028284
 protein coding gene Chr4:94846571-94874402 (-)
FVB/NJ MGP_FVBNJ_G0028251
 protein coding gene Chr4:93695693-93726719 (-)
LP/J MGP_LPJ_G0028384
 protein coding gene Chr4:98831775-98861109 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028279
 protein coding gene Chr4:111151559-111180745 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028929
 protein coding gene Chr4:97641444-97671051 (-)
PWK/PhJ MGP_PWKPhJ_G0027330
 protein coding gene Chr4:92989193-93016353 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027151
 protein coding gene Chr4:95100871-95128505 (-)
WSB/EiJ MGP_WSBEiJ_G0027683
 protein coding gene Chr4:97767274-97798401 (-)



Homology
more
  • Human Ortholog
    TM2D1, TM2 domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TM2D1, TM2 domain containing 1
  • Synonyms
    BBP
  • Links
    NCBI Gene ID: 83941
    neXtProt AC: NX_Q9BX74
    UniProt: Q9BX74

  • Chr Location
    1p31.3; chr1:61681046-61725423 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    46
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 94043 NCBI Gene Model | MGI Sequence Detail 27917 C57BL/6J ±  kb
transcript NM_053157 RefSeq | MGI Sequence Detail 1080 Not Specified  
polypeptide Q99MB3 UniProt | EBI | MGI Sequence Detail 208 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 46
    cDNA 46

    Microarray probesets 4
Other
Accession IDs
less
MGI:1916836, MGI:2145939
References
more
  • Summaries
    All 37
    Gene Ontology 3
    Phenotypes 15
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory