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Mrpl1 Gene Detail
Summary
  • Symbol
    Mrpl1
  • Name
    mitochondrial ribosomal protein L1
  • Synonyms
    2410002L03Rik, 5830418D04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137202
    NCBI Gene: 94061
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:96357357-96414586 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 47.29 cM, cytoband E3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1390 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2137202
 protein coding gene Chr5:96357352-96414586 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029764
 protein coding gene Chr5:97433047-97491152 (+)
A/J MGP_AJ_G0029730
 protein coding gene Chr5:93870722-93927884 (+)
AKR/J MGP_AKRJ_G0029676
 protein coding gene Chr5:96999367-97056818 (+)
BALB/cJ MGP_BALBcJ_G0029740
 protein coding gene Chr5:94867434-94926714 (+)
C3H/HeJ MGP_C3HHeJ_G0029463
 protein coding gene Chr5:97323202-97380738 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030195
 protein coding gene Chr5:101586948-101645736 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027430
 protein coding gene Chr5:89268117-89324139 (+)
CAST/EiJ MGP_CASTEiJ_G0028873
 protein coding gene Chr5:95910487-95968836 (+)
CBA/J MGP_CBAJ_G0029433
 protein coding gene Chr5:105105065-105166422 (+)
DBA/2J MGP_DBA2J_G0029577
 protein coding gene Chr5:94068609-94125869 (+)
FVB/NJ MGP_FVBNJ_G0029536
 protein coding gene Chr5:92899072-92956289 (+)
LP/J MGP_LPJ_G0029665
 protein coding gene Chr5:98097558-98155229 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029565
 protein coding gene Chr5:110197110-110253948 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030228
 protein coding gene Chr5:96429631-96486909 (+)
PWK/PhJ MGP_PWKPhJ_G0028592
 protein coding gene Chr5:92474367-92531928 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028427
 protein coding gene Chr5:94080879-94139098 (+)
WSB/EiJ MGP_WSBEiJ_G0028952
 protein coding gene Chr5:96745676-96803622 (+)



Homology
more
  • Human Ortholog
    MRPL1, mitochondrial ribosomal protein L1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRPL1, mitochondrial ribosomal protein L1
  • Synonyms
    BM022, L1MT, MRP-L1, uL1m
  • Links
    NCBI Gene ID: 65008
    neXtProt AC: NX_Q9BYD6
    UniProt: Q9BYD6

  • Chr Location
    4q21.1; chr4:77862830-77952785 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    720
  • Tissues
    13
  • cDNA Data
    49
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 94061 NCBI Gene Model | MGI Sequence Detail 57230 C57BL/6J ±  kb
transcript NM_053158 RefSeq | MGI Sequence Detail 3449 C57BL/6  
polypeptide Q99N96 UniProt | EBI | MGI Sequence Detail 336 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000010571 large ribosomal subunit protein uL1m
    (term hierarchy)
  • InterPro Domains
    IPR016095 Large ribosomal subunit protein uL1, 3-layer alpha/beta-sandwich domain
    IPR005879 Large ribosomal subunit protein uL1, mitochondrial
    IPR023674 Ribosomal protein uL1-like
    IPR028364 Ribosomal protein uL1/ribosomal biogenesis protein
Molecular
Reagents
less
  • All nucleic 50
    cDNA 49
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:1914850, MGI:1916955, MGI:2140906
References
more
  • Summaries
    All 39
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:297050 Cheong A, et al., Expression analysis of mammalian mitochondrial ribosomal protein genes. Gene Expr Patterns. 2020 Sep 25;38:119147
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory