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Fibcd1 Gene Detail
Summary
  • Symbol
    Fibcd1
  • Name
    fibrinogen C domain containing 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2138953
    NCBI Gene: 98970
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:31703302-31736017 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 21.89 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    808 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2138953
 protein coding gene Chr2:31703302-31736976 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025591
 protein coding gene Chr2:30193687-30230529 (-)
A/J MGP_AJ_G0025569
 protein coding gene Chr2:28941806-28975844 (-)
AKR/J MGP_AKRJ_G0025538
 protein coding gene Chr2:29936651-29971414 (-)
BALB/cJ MGP_BALBcJ_G0025565
 protein coding gene Chr2:29069008-29101921 (-)
C3H/HeJ MGP_C3HHeJ_G0025326
 protein coding gene Chr2:29851678-29885850 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026010
 protein coding gene Chr2:31134157-31179547 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023418
 protein coding gene Chr2:27686037-27719305 (-)
CAST/EiJ MGP_CASTEiJ_G0024788
 protein coding gene Chr2:29795710-29830163 (-)
CBA/J MGP_CBAJ_G0025303
 protein coding gene Chr2:32266292-32303146 (-)
DBA/2J MGP_DBA2J_G0025436
 protein coding gene Chr2:28716120-28751889 (-)
FVB/NJ MGP_FVBNJ_G0025399
 protein coding gene Chr2:28566654-28600941 (-)
LP/J MGP_LPJ_G0025522
 protein coding gene Chr2:30067415-30103767 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025429
 protein coding gene Chr2:32003027-32041224 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026068
 protein coding gene Chr2:29852064-29886585 (-)
PWK/PhJ MGP_PWKPhJ_G0024535
 protein coding gene Chr2:28606692-28640452 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024335
 protein coding gene Chr2:29991066-30023595 (-)
WSB/EiJ MGP_WSBEiJ_G0024856
 protein coding gene Chr2:30027545-30063331 (-)



Homology
more
  • Human Ortholog
    FIBCD1, fibrinogen C domain containing 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FIBCD1, fibrinogen C domain containing 1
  • Links
    NCBI Gene ID: 84929
    neXtProt AC: NX_Q8N539
    UniProt: Q8N539

  • Chr Location
    9q34.12; chr9:130902438-130940709 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice that are neutrophil-depleted show decreased susceptibility to invasive pulmonary aspergillosis, however protection is not seen in immune-competent mice and in bleomycin-induced lung injury.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    7
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    878
  • Tissues
    31
  • cDNA Data
    13
  • Literature Summary
    5
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026841 Ensembl Gene Model | MGI Sequence Detail 32716 C57BL/6J ±  kb
transcript ENSMUST00000028188 Ensembl | MGI Sequence Detail 4751 Not Applicable  
polypeptide ENSMUSP00000028188 Ensembl | MGI Sequence Detail 459 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000032818 fibrinogen C domain-containing protein 1
    (term hierarchy)
  • InterPro Domains
    IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
    IPR014716 Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1
    IPR020837 Fibrinogen, conserved site
    IPR050373 Fibrinogen C-terminal domain-containing protein
    IPR036056 Fibrinogen-like, C-terminal
  • GlyGen
    A2AV25 1 site
Molecular
Reagents
less
  • All nucleic 16
    cDNA 13
    Primer pair 3

    Microarray probesets 3
References
more
  • Summaries
    All 35
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:162220 Magdaleno S, et al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
  • Latest
    J:340669 Choi JS, et al., Single-nucleus RNA sequencing of developing superior colliculus identifies neuronal diversity and candidate mediators of circuit assembly. Cell Rep. 2023 Aug 24;42(9):113037
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory