Zfp697 MGI Mouse Gene Detail - MGI:2139736

Symbol

Zfp697
Name

zinc finger protein 697

Feature Type

protein coding gene
IDs

MGI:2139736
NCBI Gene: 242109
Alliance

gene page
Transcription Start Sites

6 TSS

Sequence Map

Chr3:98289278-98508893 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 3, 42.75 cM
Mapping Data

1 experiment

SNPs within 2kb

2056 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2139736	protein coding gene	Chr3:98289278-98661128 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0027652	protein coding gene	Chr3:99397641-99790401 (+)
A/J	MGP_AJ_G0027614	protein coding gene	Chr3:96194162-96637327 (+)
AKR/J	MGP_AKRJ_G0027581	protein coding gene	Chr3:98499861-98933990 (+)
BALB/cJ	MGP_BALBcJ_G0027624	protein coding gene	Chr3:95992118-96435120 (+)
C3H/HeJ	MGP_C3HHeJ_G0027356	protein coding gene	Chr3:98772539-99282971 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0028070	protein coding gene	Chr3:103066528-103465708 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025412	protein coding gene	Chr3:92429874-92462420 (+)
CAST/EiJ	MGP_CASTEiJ_G0026811	protein coding gene	Chr3:98075117-98444048 (+)
CBA/J	MGP_CBAJ_G0027331	protein coding gene	Chr3:106733479-107174459 (+)
DBA/2J	MGP_DBA2J_G0027474	protein coding gene	Chr3:95501531-95894656 (+)
FVB/NJ	MGP_FVBNJ_G0027443	protein coding gene	Chr3:93496876-93546322 (+)
LP/J	MGP_LPJ_G0027579	protein coding gene	Chr3:100667289-101154682 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0027469	protein coding gene	Chr3:112783017-113247859 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0028124	protein coding gene	Chr3:98117007-98496434 (+)
PWK/PhJ	MGP_PWKPhJ_G0026536	protein coding gene	Chr3:95397695-95684765 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0026358	protein coding gene	Chr3:96399250-96460378 (+)
WSB/EiJ	MGP_WSBEiJ_G0026889	protein coding gene	Chr3:98569710-99056405 (+)

Human Ortholog

ZNF697, zinc finger protein 697

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ZNF697, zinc finger protein 697
Synonyms

ZFP697
Links

HGNC:32034

NCBI Gene ID: 90874

neXtProt AC: NX_Q5TEC3

UniProt: Q5TEC3
Chr Location

1p12; chr1:119619377-119648266 (-) GRCh38

MGI Vertebrate Homology

Zfp697 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: ZNF697
Gene Tree

Zfp697

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References

1 with disease annotations

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
7 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

3
Chemically induced (other)

1
Endonuclease-mediated

1
Radiation induced

1
Genomic Mutations

2 involving Zfp697
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

11 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

6
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

782
Tissues

55
cDNA Data

12
Literature Summary

3

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

55
RefSeq

18
UniProt

2
CCDS

CCDS38564.1

Ensembl

ENSMUSG00000050064 (Evidence)
NCBI Gene

242109

			Length	Strain/Species	Flank
genomic	242109	NCBI Gene Model \| MGI Sequence Detail	219616	C57BL/6J	± kb
transcript	NM_001411512	RefSeq \| MGI Sequence Detail	6186	C57BL/6
polypeptide	Q569E7	UniProt \| EBI \| MGI Sequence Detail	569	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000018093 zinc finger protein 697

(term hierarchy)
InterPro Domains

IPR050589 Ikaros C2H2-type zinc-finger

IPR036236 Zinc finger C2H2 superfamily

IPR013087 Zinc finger C2H2-type

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All nucleic 13

cDNA 12

Primer pair 1

Microarray probesets 5

Summaries

All 31

Developmental Gene Expression 3

Diseases 1

Gene Ontology 3

Phenotypes 7
Earliest

J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Zfp697:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr30846	Chr3:98289754-98289836 (+)	517 bp
Tssr30847	Chr3:98289854-98289869 (+)	584 bp
Tssr30848	Chr3:98335088-98335109 (+)	45,821 bp
Tssr978	Chr3:98499747-98499748 (+)	210,470 bp
Tssr30849	Chr3:98506935-98506944 (+)	217,662 bp
Tssr30850	Chr3:98508202-98508215 (+)	218,931 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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