About   Help   FAQ
Cept1 Gene Detail
Summary
  • Symbol
    Cept1
  • Name
    choline/ethanolaminephosphotransferase 1
  • Synonyms
    9930118K05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2139793
    NCBI Gene: 99712
  • Alliance
    gene page
  • Transcription Start Sites
    20 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:106409576-106455118 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 46.49 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    885 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2139793
 protein coding gene Chr3:106409576-106455118 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027734
 protein coding gene Chr3:107968297-108017163 (-)
A/J MGP_AJ_G0027694
 protein coding gene Chr3:104538054-104584026 (-)
AKR/J MGP_AKRJ_G0027659
 protein coding gene Chr3:107093403-107138013 (-)
BALB/cJ MGP_BALBcJ_G0027706
 protein coding gene Chr3:104236138-104281273 (-)
C3H/HeJ MGP_C3HHeJ_G0027436
 protein coding gene Chr3:107424450-107470861 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028150
 protein coding gene Chr3:111991234-112041259 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025488
 protein coding gene Chr3:100719630-100765161 (-)
CAST/EiJ MGP_CASTEiJ_G0026892
 protein coding gene Chr3:106800276-106847279 (-)
CBA/J MGP_CBAJ_G0027411
 protein coding gene Chr3:115782228-115829806 (-)
DBA/2J MGP_DBA2J_G0027553
 protein coding gene Chr3:103744404-103791542 (-)
FVB/NJ MGP_FVBNJ_G0027521
 protein coding gene Chr3:101653467-101698524 (-)
LP/J MGP_LPJ_G0027660
 protein coding gene Chr3:109344815-109392706 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027551
 protein coding gene Chr3:121858035-121925207 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028205
 protein coding gene Chr3:106654291-106703477 (-)
PWK/PhJ MGP_PWKPhJ_G0026618
 protein coding gene Chr3:103476129-103525076 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026438
 protein coding gene Chr3:104782509-104832801 (-)
WSB/EiJ MGP_WSBEiJ_G0026972
 protein coding gene Chr3:107221586-107267534 (-)



Homology
more
  • Human Ortholog
    CEPT1, choline/ethanolamine phosphotransferase 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CEPT1, choline/ethanolamine phosphotransferase 1
  • Links
    NCBI Gene ID: 10390
    neXtProt AC: NX_Q9Y6K0
    UniProt: Q9Y6K0

  • Chr Location
    1p13.3; chr1:111139479-111185104 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Conditional homozygous knockout in skeletal muscle leads to improved glucose tolerance, increased insulin sensitivity and muscle weakness in mice fed a high fat diet.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    16
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 99712 NCBI Gene Model | MGI Sequence Detail 45543 C57BL/6J ±  kb
    transcript NM_001357819 RefSeq | MGI Sequence Detail 6053 C57BL/6  
    polypeptide Q8BGS7 UniProt | EBI | MGI Sequence Detail 416 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 16

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:2140023
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 9
      Phenotypes 14
    • Earliest
      J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
    • Latest
      J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory