Slc35f1 MGI Mouse Gene Detail - MGI:2139810 - solute carrier family 35, member F1

Symbol

Slc35f1
Name

solute carrier family 35, member F1

Feature Type

protein coding gene
IDs

MGI:2139810
NCBI Gene: 215085
Alliance

gene page
Transcription Start Sites

4 TSS

Sequence Map

Chr10:52566629-52987718 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 10, 26.79 cM
Mapping Data

1 experiment

SNPs within 2kb

10322 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2139810	protein coding gene	Chr10:52566597-52987718 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0017227	protein coding gene	Chr10:51834602-52278451 (+)
A/J	MGP_AJ_G0017203	protein coding gene	Chr10:50319523-50741775 (+)
AKR/J	MGP_AKRJ_G0017162	protein coding gene	Chr10:51294510-51735249 (+)
BALB/cJ	MGP_BALBcJ_G0017164	protein coding gene	Chr10:50426735-50872034 (+)
C3H/HeJ	MGP_C3HHeJ_G0016986	protein coding gene	Chr10:51558688-51996510 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0017623	protein coding gene	Chr10:53476981-53918671 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0015317	protein coding gene	Chr10:47496813-47912333 (+)
CAST/EiJ	MGP_CASTEiJ_G0016560	protein coding gene	Chr10:51623290-52070595 (+)
CBA/J	MGP_CBAJ_G0016959	protein coding gene	Chr10:55751354-56217638 (+)
DBA/2J	MGP_DBA2J_G0017064	protein coding gene	Chr10:49743113-50181730 (+)
FVB/NJ	MGP_FVBNJ_G0017058	protein coding gene	Chr10:49071990-49485231 (+)
LP/J	MGP_LPJ_G0017139	protein coding gene	Chr10:51915883-52348711 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0017087	protein coding gene	Chr10:57701076-58171660 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0017658	protein coding gene	Chr10:51197578-51645479 (+)
PWK/PhJ	MGP_PWKPhJ_G0016341	protein coding gene	Chr10:49583029-50011659 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0016126	protein coding gene	Chr10:50807135-51257828 (+)
WSB/EiJ	MGP_WSBEiJ_G0016625	protein coding gene	Chr10:51449302-51890668 (+)

Human Ortholog

SLC35F1, solute carrier family 35 member F1

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SLC35F1, solute carrier family 35 member F1
Synonyms

C6orf169, dJ230I3.1
Links

HGNC:21483

NCBI Gene ID: 222553

neXtProt AC: NX_Q5T1Q4

UniProt: Q5T1Q4
Chr Location

6q22.2-q22.31; chr6:117907264-118317676 (+) GRCh38

MGI Vertebrate Homology

Slc35f1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: SLC35F1
Gene Tree

Slc35f1

less

Phenotype Summary

2 phenotypes from 1 allele in 2 genetic backgrounds
15 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

6
Chemically induced (other)

1
Gene trapped

1
Radiation induced

1
Targeted

3
Genomic Mutations

2 involving Slc35f1
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

29 strains or lines available

Mice homozygous for a knock-out allele exhibit no detectable phenotypic abnormalities.

less

All GO Annotations

4
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

856
Tissues

28
cDNA Data

32
Literature Summary

1

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase slc35f1

less

All Sequences

41
RefSeq

2
UniProt

1
CCDS

CCDS23843.1

Ensembl

ENSMUSG00000038602 (Evidence)
NCBI Gene

215085

			Length	Strain/Species	Flank
genomic	ENSMUSG00000038602	Ensembl Gene Model \| MGI Sequence Detail	421090	C57BL/6J	± kb
transcript	ENSMUST00000105473	Ensembl \| MGI Sequence Detail	4941	Not Applicable
polypeptide	ENSMUSP00000101113	Ensembl \| MGI Sequence Detail	408	Not Applicable

less

UniProt

1 Sequence
Protein Ontology

PR:000015105 solute carrier family 35 member F1

(term hierarchy)
InterPro Domains

IPR052221 SLC35F Solute Transporter

IPR009262 Solute carrier family 35 member SLC35F1/F2/F6

less

All nucleic 33

cDNA 32

Primer pair 1

Microarray probesets 4

Summaries

All 38

Developmental Gene Expression 1

Gene Ontology 3

Phenotypes 15
Earliest

J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Slc35f1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr93309	Chr10:52566592-52566650 (+)	-8 bp
Tssr93310	Chr10:52566670-52566682 (+)	47 bp
Tssr93311	Chr10:52566691-52566698 (+)	66 bp
Tssr93312	Chr10:52637031-52637047 (+)	70,410 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24