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Zfp518b Gene Detail
Summary
  • Symbol
    Zfp518b
  • Name
    zinc finger protein 518B
  • Synonyms
    6820424L24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140750
    NCBI Gene: 100515
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:38825828-38842120 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 20.77 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    520 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140750
 protein coding gene Chr5:38825827-38842169 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029514
 protein coding gene Chr5:37095486-37114115 (-)
A/J MGP_AJ_G0029480
 protein coding gene Chr5:35845175-35861444 (-)
AKR/J MGP_AKRJ_G0029430
 protein coding gene Chr5:37190036-37208083 (-)
BALB/cJ MGP_BALBcJ_G0029491
 protein coding gene Chr5:36335479-36351784 (-)
C3H/HeJ MGP_C3HHeJ_G0029214
 protein coding gene Chr5:37181101-37197426 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029945
 protein coding gene Chr5:39051146-39067463 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027183
 protein coding gene Chr5:33510009-33527080 (-)
CAST/EiJ MGP_CASTEiJ_G0028622
 protein coding gene Chr5:36359601-36376534 (-)
CBA/J MGP_CBAJ_G0029181
 protein coding gene Chr5:39972188-39988485 (-)
DBA/2J MGP_DBA2J_G0029328
 protein coding gene Chr5:35974041-35990351 (-)
FVB/NJ MGP_FVBNJ_G0029287
 protein coding gene Chr5:35469146-35485697 (-)
LP/J MGP_LPJ_G0029414
 protein coding gene Chr5:37550886-37568240 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029317
 protein coding gene Chr5:40693608-40710839 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029978
 protein coding gene Chr5:36688124-36704460 (-)
PWK/PhJ MGP_PWKPhJ_G0028346
 protein coding gene Chr5:35145755-35162047 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028180
 protein coding gene Chr5:36138780-36157241 (-)
WSB/EiJ MGP_WSBEiJ_G0028703
 protein coding gene Chr5:36770081-36789178 (-)



Homology
more
  • Human Ortholog
    ZNF518B, zinc finger protein 518B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF518B, zinc finger protein 518B
  • Links
    NCBI Gene ID: 85460
    neXtProt AC: NX_Q9C0D4
    UniProt: Q9C0D4

  • Chr Location
    4p16.1; chr4:10439880-10461365 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    26 phenotype references
  • All Mutations and Alleles
    23
  • Chemically induced (ENU)
    1
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Gene trapped
    15
  • Radiation induced
    2
  • Spontaneous
    1
  • Targeted
    1
  • Genomic Mutations
    6 involving Zfp518b
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    36 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    77
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100515 NCBI Gene Model | MGI Sequence Detail 16293 C57BL/6J ±  kb
transcript NM_001081144 RefSeq | MGI Sequence Detail 6832 C57BL/6  
polypeptide B2RRE4 UniProt | EBI | MGI Sequence Detail 1077 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 77
    cDNA 77

    Microarray probesets 5
Other
Accession IDs
less
MGI:2140953
References
more
  • Summaries
    All 48
    Diseases 1
    Gene Ontology 3
    Phenotypes 26
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory