Rell1 MGI Mouse Gene Detail - MGI:2140767

Symbol

Rell1
Name

RELT-like 1

Feature Type

protein coding gene
IDs

MGI:2140767
NCBI Gene: 100532
Alliance

gene page
Transcription Start Sites

5 TSS

Sequence Map

Chr5:64066240-64126240 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 5, 32.80 cM
Mapping Data

1 experiment

SNPs within 2kb

2175 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2140767	protein coding gene	Chr5:64047296-64126240 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0029564	protein coding gene	Chr5:63475727-63537961 (-)
A/J	MGP_AJ_G0029532	protein coding gene	Chr5:61110959-61172281 (-)
AKR/J	MGP_AKRJ_G0029480	protein coding gene	Chr5:63014376-63076108 (-)
BALB/cJ	MGP_BALBcJ_G0029541	protein coding gene	Chr5:61791966-61852478 (-)
C3H/HeJ	MGP_C3HHeJ_G0029264	protein coding gene	Chr5:63387874-63452635 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0029995	protein coding gene	Chr5:66110864-66179020 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0027235	protein coding gene	Chr5:57223409-57285121 (-)
CAST/EiJ	MGP_CASTEiJ_G0028672	protein coding gene	Chr5:62452622-62519123 (-)
CBA/J	MGP_CBAJ_G0029233	protein coding gene	Chr5:68212932-68277368 (-)
DBA/2J	MGP_DBA2J_G0029379	protein coding gene	Chr5:61139405-61210047 (-)
FVB/NJ	MGP_FVBNJ_G0029339	protein coding gene	Chr5:60325695-60386163 (-)
LP/J	MGP_LPJ_G0029464	protein coding gene	Chr5:63934697-64001233 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0029367	protein coding gene	Chr5:71163185-71229415 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0030028	protein coding gene	Chr5:62727941-62793195 (-)
PWK/PhJ	MGP_PWKPhJ_G0028396	protein coding gene	Chr5:60121379-60182739 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0028230	protein coding gene	Chr5:62074274-62135843 (-)
WSB/EiJ	MGP_WSBEiJ_G0028753	protein coding gene	Chr5:62923667-62992169 (-)

Human Ortholog

RELL1, RELT like 1

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

RELL1, RELT like 1
Links

HGNC:27379

NCBI Gene ID: 768211

neXtProt AC: NX_Q8IUW5

UniProt: Q8IUW5
Chr Location

chr4:37586304-37686376 (-) GRCh38

MGI Vertebrate Homology

Rell1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: RELL1
Gene Tree

Rell1

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Phenotype Summary

4 phenotypes from 1 allele in 1 genetic background
24 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

15
Chemically induced (other)

2
Endonuclease-mediated

2
Gene trapped

8
Radiation induced

1
Spontaneous

1
Targeted

1
Genomic Mutations

4 involving Rell1
Incidental Mutations

APF
Find Mice (IMSR)

35 strains or lines available

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All GO Annotations

8
GO References

5

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

708
Tissues

1
cDNA Data

62
Literature Summary

1

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GENSAT

GEO

Expression Atlas
Other Vertebrate Links

Xenbase rell1

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All Sequences

58
RefSeq

8
UniProt

2
CCDS

CCDS39093.1

Ensembl

ENSMUSG00000047881 (Evidence)
NCBI Gene

100532

			Length	Strain/Species	Flank
genomic	ENSMUSG00000047881	Ensembl Gene Model \| MGI Sequence Detail	60001	C57BL/6J	± kb
transcript	ENSMUST00000154169	Ensembl \| MGI Sequence Detail	3241	Not Applicable
polypeptide	ENSMUSP00000118125	Ensembl \| MGI Sequence Detail	272	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000013877 RELT-like protein 1

(term hierarchy)
InterPro Domains

IPR042315 RELT-like protein 1

IPR022248 TNF receptor family, RELT

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All nucleic 63

cDNA 62

Primer pair 1

Microarray probesets 4

Summaries

All 48

Developmental Gene Expression 1

Gene Ontology 5

Phenotypes 24
Earliest

J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Rell1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr51056	Chr5:64126210-64126244 (-)	13 bp
Tssr51055	Chr5:64126194-64126207 (-)	39 bp
Tssr51054	Chr5:64126150-64126183 (-)	73 bp
Tssr51053	Chr5:64110982-64110991 (-)	15,253 bp
Tssr51052	Chr5:64096894-64096930 (-)	29,328 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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