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Sdad1 Gene Detail
Summary
  • Symbol
    Sdad1
  • Name
    SDA1 domain containing 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140779
    NCBI Gene: 231452
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:92431869-92457883 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 46.42 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    905 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140779
 protein coding gene Chr5:92431869-92458338 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029747
 protein coding gene Chr5:93460373-93489689 (-)
A/J MGP_AJ_G0029713
 protein coding gene Chr5:89749803-89776848 (-)
AKR/J MGP_AKRJ_G0029659
 protein coding gene Chr5:92684123-92712008 (-)
BALB/cJ MGP_BALBcJ_G0029723
 protein coding gene Chr5:90632349-90661226 (-)
C3H/HeJ MGP_C3HHeJ_G0029446
 protein coding gene Chr5:93089791-93118719 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030177
 protein coding gene Chr5:97174284-97201768 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027413
 protein coding gene Chr5:85397713-85425044 (-)
CAST/EiJ MGP_CASTEiJ_G0028856
 protein coding gene Chr5:92465524-92495821 (-)
CBA/J MGP_CBAJ_G0029416
 protein coding gene Chr5:100543534-100574133 (-)
DBA/2J MGP_DBA2J_G0029560
 protein coding gene Chr5:89796335-89824204 (-)
FVB/NJ MGP_FVBNJ_G0029519
 protein coding gene Chr5:88641290-88669354 (-)
LP/J MGP_LPJ_G0029648
 protein coding gene Chr5:93830261-93858099 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029548
 protein coding gene Chr5:105454122-105483488 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030211
 protein coding gene Chr5:92216307-92243466 (-)
PWK/PhJ MGP_PWKPhJ_G0028575
 protein coding gene Chr5:88860537-88889329 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028410
 protein coding gene Chr5:91578973-91607710 (-)
WSB/EiJ MGP_WSBEiJ_G0028935
 protein coding gene Chr5:92672636-92709456 (-)



Homology
more
  • Human Ortholog
    SDAD1, SDA1 domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SDAD1, SDA1 domain containing 1
  • Synonyms
    Sda1
  • Links
    NCBI Gene ID: 55153
    neXtProt AC: NX_Q9NVU7
    UniProt: Q9NVU7

  • Chr Location
    4q21.1; chr4:75940950-75990962 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from multigenic genotypes
    12 phenotype references
Mice homozygous for ENU-induced alleles Dmp1m1Btlr, Sdad1m1Btlr, and Ptpn11m1Btlr exhibit decreased bone mineral density and short tibia.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    6
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    105
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 231452 NCBI Gene Model | MGI Sequence Detail 26015 C57BL/6J ±  kb
transcript NM_172713 RefSeq | MGI Sequence Detail 5020 C57BL/6  
polypeptide Q80UZ2 UniProt | EBI | MGI Sequence Detail 687 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 105
    cDNA 105

    Microarray probesets 5
Other
Accession IDs
less
MGI:2141211
References
more
  • Summaries
    All 38
    Gene Ontology 6
    Phenotypes 12
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:309727 Rios JJ, et al., Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice. J Bone Miner Res. 2021 Aug;36(8):1548-1565
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory