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Ino80e Gene Detail
Summary
  • Symbol
    Ino80e
  • Name
    INO80 complex subunit E
  • Synonyms
    Ccdc95
  • Feature Type
    protein coding gene
  • IDs
    MGI:2141881
    NCBI Gene: 233875
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:126450756-126461544 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 69.25 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    228 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2141881
 protein coding gene Chr7:126450132-126461549 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033004
 protein coding gene Chr7:131157361-131168778 (-)
A/J MGP_AJ_G0032987
 protein coding gene Chr7:127676786-127688209 (-)
AKR/J MGP_AKRJ_G0032919
 protein coding gene Chr7:130912091-130923508 (-)
BALB/cJ MGP_BALBcJ_G0032992
 protein coding gene Chr7:127340298-127351715 (-)
C3H/HeJ MGP_C3HHeJ_G0032702
 protein coding gene Chr7:130850251-130861668 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033498
 protein coding gene Chr7:136257810-136269227 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030470
 protein coding gene Chr7:128870699-128881886 (-)
CAST/EiJ MGP_CASTEiJ_G0032031
 protein coding gene Chr7:122636181-122647640 (-)
CBA/J MGP_CBAJ_G0032675
 protein coding gene Chr7:140844004-140857999 (-)
DBA/2J MGP_DBA2J_G0032827
 protein coding gene Chr7:125652348-125663765 (-)
FVB/NJ MGP_FVBNJ_G0032780
 protein coding gene Chr7:125502529-125514967 (-)
LP/J MGP_LPJ_G0032921
 protein coding gene Chr7:132623526-132634943 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032812
 protein coding gene Chr7:142014098-142026827 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033517
 protein coding gene Chr7:129921903-129933326 (-)
PWK/PhJ MGP_PWKPhJ_G0031738
 protein coding gene Chr7:118646748-118658251 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031584
 protein coding gene Chr7:116767640-116779068 (-)
WSB/EiJ MGP_WSBEiJ_G0032143
 protein coding gene Chr7:130901224-130912506 (-)



Homology
more
  • Human Ortholog
    INO80E, INO80 complex subunit E
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    INO80E, INO80 complex subunit E
  • Synonyms
    CCDC95
  • Links
    NCBI Gene ID: 283899
    neXtProt AC: NX_Q8NBZ0
    UniProt: Q8NBZ0

  • Chr Location
    16p11.2; chr16:29995715-30005793 (+)  GRCh38
Human Diseases
less
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    44 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    2
  • cDNA Data
    7
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 233875 NCBI Gene Model | MGI Sequence Detail 10789 C57BL/6J ±  kb
    transcript NM_001370765 RefSeq | MGI Sequence Detail 1403 C57BL/6  
    polypeptide NP_001357694 RefSeq | MGI Sequence Detail 340 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      11 Sequences
    • InterPro Domains
      IPR026678 INO80 complex subunit E
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 8

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:2142073
    References
    more
    • Summaries
      All 64
      Developmental Gene Expression 2
      Diseases 3
      Gene Ontology 2
      Phenotypes 44
    • Earliest
      J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
    • Latest
      J:349484 Henis M, et al., The autism susceptibility kinase, TAOK2, phosphorylates eEF2 and modulates translation. Sci Adv. 2024 Apr 12;10(15):eadf7001
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory