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Scaf1 Gene Detail
Summary
  • Symbol
    Scaf1
  • Name
    SR-related CTD-associated factor 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2141980
    NCBI Gene: 233208
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:44652372-44665537 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 29.07 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    272 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2141980
 protein coding gene Chr7:44652372-44665787 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032193
 protein coding gene Chr7:45228768-45243811 (-)
A/J MGP_AJ_G0032172
 protein coding gene Chr7:44370555-44387672 (-)
AKR/J MGP_AKRJ_G0032108
 protein coding gene Chr7:45598434-45612092 (-)
BALB/cJ MGP_BALBcJ_G0032184
 protein coding gene Chr7:44368767-44381893 (-)
C3H/HeJ MGP_C3HHeJ_G0031900
 protein coding gene Chr7:46099002-46113666 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032676
 protein coding gene Chr7:47488569-47513264 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029690
 protein coding gene Chr7:46937864-46951159 (-)
CAST/EiJ MGP_CASTEiJ_G0031228
 protein coding gene Chr7:37469543-37482987 (-)
CBA/J MGP_CBAJ_G0031864
 protein coding gene Chr7:49051127-49064866 (-)
DBA/2J MGP_DBA2J_G0032022
 protein coding gene Chr7:44042209-44056117 (-)
FVB/NJ MGP_FVBNJ_G0031973
 protein coding gene Chr7:43820267-43834781 (-)
LP/J MGP_LPJ_G0032100
 protein coding gene Chr7:45903730-45917155 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032010
 protein coding gene Chr7:47773057-47787460 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032692
 protein coding gene Chr7:44817077-44830458 (-)
PWK/PhJ MGP_PWKPhJ_G0030951
 protein coding gene Chr7:37406533-37420197 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030788
 protein coding gene Chr7:32824014-32837509 (-)
WSB/EiJ MGP_WSBEiJ_G0031345
 protein coding gene Chr7:45293933-45309310 (-)



Homology
more
  • Human Ortholog
    SCAF1, SR-related CTD associated factor 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SCAF1, SR-related CTD associated factor 1
  • Synonyms
    SRA1
  • Links
    NCBI Gene ID: 58506
    neXtProt AC: NX_Q9H7N4
    UniProt: Q9H7N4

  • Chr Location
    19q13.33; chr19:49640465-49658642 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    89
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 233208 NCBI Gene Model | MGI Sequence Detail 13166 C57BL/6J ±  kb
transcript NM_001400821 RefSeq | MGI Sequence Detail 4789 C57BL/6  
polypeptide Q5U4C3 UniProt | EBI | MGI Sequence Detail 1256 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 89
    cDNA 89

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:274509 Sapkota M, et al., Malondialdehyde-acetaldehyde (MAA) adducted surfactant protein induced lung inflammation is mediated through scavenger receptor a (SR-A1). Respir Res. 2017 Feb 13;18(1):36
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory