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Vat1l Gene Detail
Summary
  • Symbol
    Vat1l
  • Name
    vesicle amine transport protein 1 like
  • Synonyms
    mKIAA1576
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142534
    NCBI Gene: 270097
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:114932352-115100811 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 60.62 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    5246 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2142534
 protein coding gene Chr8:114932307-115100814 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034159
 protein coding gene Chr8:117169722-117345794 (+)
A/J MGP_AJ_G0034139
 protein coding gene Chr8:112374114-112576015 (+)
AKR/J MGP_AKRJ_G0034066
 protein coding gene Chr8:115681237-115855682 (+)
BALB/cJ MGP_BALBcJ_G0034133
 protein coding gene Chr8:112589261-112755631 (+)
C3H/HeJ MGP_C3HHeJ_G0033844
 protein coding gene Chr8:116371210-116549522 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034653
 protein coding gene Chr8:121184706-121368522 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031595
 protein coding gene Chr8:105400177-105562657 (+)
CAST/EiJ MGP_CASTEiJ_G0033171
 protein coding gene Chr8:116100802-116274087 (+)
CBA/J MGP_CBAJ_G0033817
 protein coding gene Chr8:125451460-125656878 (+)
DBA/2J MGP_DBA2J_G0033973
 protein coding gene Chr8:111629054-111802133 (+)
FVB/NJ MGP_FVBNJ_G0033916
 protein coding gene Chr8:110619806-110787827 (+)
LP/J MGP_LPJ_G0034062
 protein coding gene Chr8:117316799-117490683 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033963
 protein coding gene Chr8:128214862-128404593 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034671
 protein coding gene Chr8:115723051-115906902 (+)
PWK/PhJ MGP_PWKPhJ_G0032873
 protein coding gene Chr8:111331610-111495607 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032713
 protein coding gene Chr8:114373177-114571235 (+)
WSB/EiJ MGP_WSBEiJ_G0033287
 protein coding gene Chr8:116418052-116597240 (+)



Homology
more
  • Human Ortholog
    VAT1L, vesicle amine transport 1 like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    VAT1L, vesicle amine transport 1 like
  • Links
    NCBI Gene ID: 57687
    neXtProt AC: NX_Q9HCJ6
    UniProt: Q9HCJ6

  • Chr Location
    16q23.1; chr16:77788564-77980107 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1022
  • Tissues
    67
  • cDNA Data
    40
  • Literature Summary
    6
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000046844 Ensembl Gene Model | MGI Sequence Detail 168460 C57BL/6J ±  kb
transcript ENSMUST00000049509 Ensembl | MGI Sequence Detail 3666 Not Applicable  
polypeptide ENSMUSP00000053431 Ensembl | MGI Sequence Detail 417 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000017265 synaptic vesicle membrane protein VAT-1-like
    (term hierarchy)
  • EC
    1.-.-.-
  • InterPro Domains
    IPR013154 Alcohol dehydrogenase-like, N-terminal
    IPR011032 GroES-like superfamily
    IPR036291 NAD(P)-binding domain superfamily
    IPR020843 Polyketide synthase, enoylreductase domain
    IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site
    IPR052100 Synaptic vesicle ATPase and mitochondrial regulator
  • GlyGen
    Q80TB8 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 42
    cDNA 42

    Microarray probesets 4
References
more
  • Summaries
    All 33
    Developmental Gene Expression 6
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory