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Rpp25 Gene Detail
Summary
  • Symbol
    Rpp25
  • Name
    ribonuclease P/MRP 25 subunit
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143151
    NCBI Gene: 102614
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:57411385-57412730 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 31.05 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    113 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2143151
 protein coding gene Chr9:57411309-57412731 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034866
 protein coding gene Chr9:56716342-56717689 (+)
A/J MGP_AJ_G0034847
 protein coding gene Chr9:54887977-54889324 (+)
AKR/J MGP_AKRJ_G0034776
 protein coding gene Chr9:56143781-56145128 (+)
BALB/cJ MGP_BALBcJ_G0034839
 protein coding gene Chr9:54673075-54674420 (+)
C3H/HeJ MGP_C3HHeJ_G0034549
 protein coding gene Chr9:56633715-56635062 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035358
 protein coding gene Chr9:58297010-58298355 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032269
 protein coding gene Chr9:54196931-54198256 (+)
CAST/EiJ MGP_CASTEiJ_G0033870
 protein coding gene Chr9:56722237-56723582 (+)
CBA/J MGP_CBAJ_G0034520
 protein coding gene Chr9:60335660-60337005 (+)
DBA/2J MGP_DBA2J_G0034679
 protein coding gene Chr9:54753984-54755331 (+)
FVB/NJ MGP_FVBNJ_G0034621
 protein coding gene Chr9:53979970-53981317 (+)
LP/J MGP_LPJ_G0034762
 protein coding gene Chr9:57013696-57015043 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034664
 protein coding gene Chr9:61825436-61826783 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035380
 protein coding gene Chr9:56170790-56172137 (+)
PWK/PhJ MGP_PWKPhJ_G0033575
 protein coding gene Chr9:54785981-54787368 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033409
 protein coding gene Chr9:56464401-56465748 (+)
WSB/EiJ MGP_WSBEiJ_G0033983
 protein coding gene Chr9:56103265-56104612 (+)



Homology
more
  • Human Ortholog
    RPP25, ribonuclease P and MRP subunit p25
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPP25, ribonuclease P and MRP subunit p25
  • Links
    NCBI Gene ID: 54913
    neXtProt AC: NX_Q9BUL9
    UniProt: Q9BUL9

  • Chr Location
    15q24.2; chr15:74954418-74956772 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    838
  • Tissues
    98
  • cDNA Data
    14
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 102614 NCBI Gene Model | MGI Sequence Detail 1346 C57BL/6J ±  kb
transcript NM_133982 RefSeq | MGI Sequence Detail 1361 Not Specified  
polypeptide Q91WE3 UniProt | EBI | MGI Sequence Detail 199 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 14
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 31
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:88304 Xiao S, et al., Eukaryotic ribonuclease P: a plurality of ribonucleoprotein enzymes. Annu Rev Biochem. 2002;71:165-89
  • Latest
    J:341393 Cheffer A, et al., DOT1L deletion impairs the development of cortical parvalbumin-expressing interneurons. Cereb Cortex. 2023 Sep 26;33(19):10272-10285
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory