Zfp809 MGI Mouse Gene Detail - MGI:2143362

Symbol

Zfp809
Name

zinc finger protein 809

Feature Type

protein coding gene
IDs

MGI:2143362
NCBI Gene: 235047
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr9:22137010-22154650 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 9, 8.65 cM
Mapping Data

1 experiment

SNPs within 2kb

612 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2143362	protein coding gene	Chr9:22136980-22165413 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0034482	protein coding gene	Chr9:19523195-19540720 (+)
A/J	MGP_AJ_G0034460	protein coding gene	Chr9:19133404-19151846 (+)
AKR/J	MGP_AKRJ_G0034386	protein coding gene	Chr9:19507612-19535122 (+)
BALB/cJ	MGP_BALBcJ_G0034451	protein coding gene	Chr9:19015457-19033404 (+)
C3H/HeJ	MGP_C3HHeJ_G0034163	protein coding gene	Chr9:19815102-19842752 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0034972	protein coding gene	Chr9:20301846-20319034 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0031902	protein coding gene	Chr9:18248707-18264327 (+)
CAST/EiJ	MGP_CASTEiJ_G0033486	protein coding gene	Chr9:19675853-19693563 (+)
CBA/J	MGP_CBAJ_G0034136	protein coding gene	Chr9:21086853-21111369 (+)
DBA/2J	MGP_DBA2J_G0034294	protein coding gene	Chr9:19109387-19127276 (+)
FVB/NJ	MGP_FVBNJ_G0034237	protein coding gene	Chr9:18665964-18682180 (+)
LP/J	MGP_LPJ_G0034380	protein coding gene	Chr9:19714133-19731165 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0034281	protein coding gene	Chr9:22659380-22679072 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0034992	protein coding gene	Chr9:19476890-19495079 (+)
PWK/PhJ	MGP_PWKPhJ_G0033191	protein coding gene	Chr9:19116964-19134387 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0033025	protein coding gene	Chr9:19518475-19536251 (+)
WSB/EiJ	MGP_WSBEiJ_G0033601	protein coding gene	Chr9:19210450-19228459 (+)

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Gene Tree

Zfp809

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Phenotype Summary

1 phenotype from 3 alleles in 3 genetic backgrounds
10 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

46
Endonuclease-mediated

1
Gene trapped

43
Targeted

2
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

68 strains or lines available

Mice homozygous for a knock-out allele exhibit increased expression of VL30-pro endogenous retroviruses (ERV) elements.

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All GO Annotations

14
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

767
Tissues

40
cDNA Data

29
Literature Summary

4

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

57
RefSeq

11
UniProt

5
CCDS

CCDS40560.1, CCDS90519.1

Ensembl

ENSMUSG00000057982 (Evidence)
NCBI Gene

235047

			Length	Strain/Species	Flank
genomic	ENSMUSG00000057982	Ensembl Gene Model \| MGI Sequence Detail	17641	C57BL/6J	± kb
transcript	ENSMUST00000072465	Ensembl \| MGI Sequence Detail	1425	Not Applicable
polypeptide	ENSMUSP00000072286	Ensembl \| MGI Sequence Detail	402	Not Applicable

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UniProt

5 Sequences
InterPro Domains

IPR036051 KRAB domain superfamily

IPR001909 Krueppel-associated box

IPR050169 Krueppel C2H2-type zinc-finger

IPR039938 Transcription factor Sp4-like

IPR036236 Zinc finger C2H2 superfamily

IPR013087 Zinc finger C2H2-type

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All nucleic 32

Genomic 2

cDNA 29

Primer pair 1

Microarray probesets 3

Summaries

All 33

Developmental Gene Expression 4

Gene Ontology 4

Phenotypes 10
Earliest

J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
Latest

J:219938 Wolf G, et al., The KRAB zinc finger protein ZFP809 is required to initiate epigenetic silencing of endogenous retroviruses. Genes Dev. 2015 Mar 1;29(5):538-54

TSS for Zfp809:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr84083	Chr9:22136998-22137026 (+)	2 bp
Tssr84084	Chr9:22137029-22137056 (+)	33 bp
Tssr84085	Chr9:22151101-22151115 (+)	14,098 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/29/2024 MGI 6.24