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Stradb Gene Detail
Summary
  • Symbol
    Stradb
  • Name
    STE20-related kinase adaptor beta
  • Synonyms
    Als2cr2, D1Ucla2, PRO1038
  • Feature Type
    protein coding gene
  • IDs
    MGI:2144047
    NCBI Gene: 227154
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:59012681-59034281 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 29.20 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    560 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2144047
 protein coding gene Chr1:59012681-59034874 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016060
 protein coding gene Chr1:58916018-58942219 (+)
A/J MGP_AJ_G0016043
 protein coding gene Chr1:56860451-56891059 (+)
AKR/J MGP_AKRJ_G0015999
 protein coding gene Chr1:58460555-58482420 (+)
BALB/cJ MGP_BALBcJ_G0015998
 protein coding gene Chr1:56910936-56932922 (+)
C3H/HeJ MGP_C3HHeJ_G0015830
 protein coding gene Chr1:58709180-58733659 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016451
 protein coding gene Chr1:61241553-61264543 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014172
 protein coding gene Chr1:52695536-52717176 (+)
CAST/EiJ MGP_CASTEiJ_G0015412
 protein coding gene Chr1:57844566-57868226 (+)
CBA/J MGP_CBAJ_G0015802
 protein coding gene Chr1:63152806-63180249 (+)
DBA/2J MGP_DBA2J_G0015903
 protein coding gene Chr1:56292468-56314649 (+)
FVB/NJ MGP_FVBNJ_G0015905
 protein coding gene Chr1:55601963-55623870 (+)
LP/J MGP_LPJ_G0015975
 protein coding gene Chr1:59799557-59823218 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015925
 protein coding gene Chr1:66100347-66123167 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016498
 protein coding gene Chr1:58368919-58392041 (+)
PWK/PhJ MGP_PWKPhJ_G0015199
 protein coding gene Chr1:55633192-55655093 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014979
 protein coding gene Chr1:57892514-57921671 (+)
WSB/EiJ MGP_WSBEiJ_G0015475
 protein coding gene Chr1:58067276-58089859 (+)



Homology
more
  • Human Ortholog
    STRADB, STE20 related adaptor beta
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    STRADB, STE20 related adaptor beta
  • Synonyms
    ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK, PRO1038
  • Links
    NCBI Gene ID: 55437
    neXtProt AC: NX_Q9C0K7
    UniProt: Q9C0K7

  • Chr Location
    2q33.1; chr2:201387858-201480846 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    821
  • Tissues
    37
  • cDNA Data
    54
  • Literature Summary
    6
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 227154 NCBI Gene Model | MGI Sequence Detail 21601 C57BL/6J ±  kb
transcript NM_172656 RefSeq | MGI Sequence Detail 2387 ZRU/MplStud  
polypeptide Q8K4T3 UniProt | EBI | MGI Sequence Detail 418 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 56
    Genomic 1
    cDNA 54
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-5717, MGI:91858
References
more
  • Summaries
    All 49
    Developmental Gene Expression 6
    Gene Ontology 7
    Phenotypes 12
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory