Sec14l4 MGI Mouse Gene Detail - MGI:2144095 - SEC14-like lipid binding 4

Symbol

Sec14l4
Name

SEC14-like lipid binding 4

Feature Type

protein coding gene
IDs

MGI:2144095
NCBI Gene: 103655
Alliance

gene page
Transcription Start Sites

5 TSS

Sequence Map

Chr11:3981462-3998024 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 2.84 cM
Mapping Data

1 experiment

SNPs within 2kb

464 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2144095	protein coding gene	Chr11:3981377-3998426 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0017971	protein coding gene	Chr11:947058-965198 (+)
A/J	MGP_AJ_G0017944	protein coding gene	Chr11:977253-993488 (+)
AKR/J	MGP_AKRJ_G0017908	protein coding gene	Chr11:1024066-1043617 (+)
BALB/cJ	MGP_BALBcJ_G0017912	protein coding gene	Chr11:939767-956083 (+)
C3H/HeJ	MGP_C3HHeJ_G0017725	protein coding gene	Chr11:923108-941695 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0018365	protein coding gene	Chr11:1030788-1048574 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0016023	protein coding gene	Chr11:851927-870800 (+)
CAST/EiJ	MGP_CASTEiJ_G0017287	protein coding gene	Chr11:883768-899146 (+)
CBA/J	MGP_CBAJ_G0017700	protein coding gene	Chr11:1254220-1270511 (+)
DBA/2J	MGP_DBA2J_G0017811	protein coding gene	Chr11:870404-889741 (+)
FVB/NJ	MGP_FVBNJ_G0017802	protein coding gene	Chr11:907788-924135 (+)
LP/J	MGP_LPJ_G0017881	protein coding gene	Chr11:1058616-1078271 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0017828	protein coding gene	Chr11:954224-969950 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0018404	protein coding gene	Chr11:1024459-1040543 (+)
PWK/PhJ	MGP_PWKPhJ_G0017068	protein coding gene	Chr11:863226-880847 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0016864	protein coding gene	Chr11:973131-988644 (+)
WSB/EiJ	MGP_WSBEiJ_G0017341	protein coding gene	Chr11:895290-912505 (+)

Human Ortholog

SEC14L4, SEC14 like lipid binding 4

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SEC14L4, SEC14 like lipid binding 4
Synonyms

TAP3
Links

HGNC:20627

NCBI Gene ID: 284904

neXtProt AC: NX_Q9UDX3

UniProt: Q9UDX3
Chr Location

22q12.2; chr22:30488902-30505711 (-) GRCh38

MGI Vertebrate Homology

Sec14l4 stringent orthology
1 human;1 mouse;1 zebrafish
HCOP

vertebrate homology predictions: SEC14L4
Gene Tree

Sec14l4

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Phenotype Summary

6 phenotype references

All Mutations and Alleles

4
Gene trapped

1
Targeted

3
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

18 strains or lines available

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All GO Annotations

2
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

28

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

45
RefSeq

8
UniProt

1
CCDS

CCDS24374.1

Ensembl

ENSMUSG00000019368 (Evidence)
NCBI Gene

103655

			Length	Strain/Species	Flank
genomic	ENSMUSG00000019368	Ensembl Gene Model \| MGI Sequence Detail	16563	C57BL/6J	± kb
transcript	ENSMUST00000019512	Ensembl \| MGI Sequence Detail	2956	Not Applicable
polypeptide	ENSMUSP00000019512	Ensembl \| MGI Sequence Detail	403	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000014579 SEC14-like protein 4

(term hierarchy)
InterPro Domains

IPR001251 CRAL-TRIO lipid binding domain

IPR036865 CRAL-TRIO lipid binding domain superfamily

IPR011074 CRAL/TRIO, N-terminal domain

IPR036273 CRAL/TRIO, N-terminal domain superfamily

IPR009038 GOLD domain

IPR036598 GOLD domain superfamily

IPR051064 SEC14-like and CRAL-TRIO domain-containing protein

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All nucleic 28

cDNA 28

Microarray probesets 3

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MGI:2144552

Summaries

All 29

Gene Ontology 2

Phenotypes 6
Earliest

J:33182 Hirashima S, et al., Molecular cloning and characterization of cDNA for eukaryotic transcription factor S-II. J Biol Chem. 1988 Mar 15;263(8):3858-63
Latest

J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

TSS for Sec14l4:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr100081	Chr11:3981457-3981498 (+)	16 bp
Tssr100082	Chr11:3981606-3981614 (+)	148 bp
Tssr100083	Chr11:3981770-3981833 (+)	340 bp
Tssr100084	Chr11:3985068-3985101 (+)	3,623 bp
Tssr100085	Chr11:3996318-3996319 (+)	14,857 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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