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Lhfpl2 Gene Detail
Summary
  • Symbol
    Lhfpl2
  • Name
    lipoma HMGIC fusion partner-like 2
  • Synonyms
    mKIAA0206, vgim
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145236
    NCBI Gene: 218454
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:94194304-94331917 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 49.03 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4447 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2145236
 protein coding gene Chr13:94193659-94331918 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020830
 protein coding gene Chr13:95453170-95600066 (+)
A/J MGP_AJ_G0020784
 protein coding gene Chr13:91883581-92021657 (+)
AKR/J MGP_AKRJ_G0020758
 protein coding gene Chr13:94693305-94836272 (+)
BALB/cJ MGP_BALBcJ_G0020781
 protein coding gene Chr13:92538583-92687724 (+)
C3H/HeJ MGP_C3HHeJ_G0020574
 protein coding gene Chr13:94399804-94546726 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021217
 protein coding gene Chr13:98362917-98511551 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018786
 protein coding gene Chr13:87730603-87869599 (+)
CAST/EiJ MGP_CASTEiJ_G0020093
 protein coding gene Chr13:93645242-93786788 (+)
CBA/J MGP_CBAJ_G0020533
 protein coding gene Chr13:102285393-102438699 (+)
DBA/2J MGP_DBA2J_G0020658
 protein coding gene Chr13:91677726-91815224 (+)
FVB/NJ MGP_FVBNJ_G0020639
 protein coding gene Chr13:90458844-90601331 (+)
LP/J MGP_LPJ_G0020733
 protein coding gene Chr13:95559494-95700329 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020667
 protein coding gene Chr13:102747996-102895853 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021257
 protein coding gene Chr13:94086024-94230172 (+)
PWK/PhJ MGP_PWKPhJ_G0019845
 protein coding gene Chr13:90392840-90536563 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019669
 protein coding gene Chr13:90350078-90492949 (+)
WSB/EiJ MGP_WSBEiJ_G0020150
 protein coding gene Chr13:94573120-94717238 (+)



Homology
more
  • Human Ortholog
    LHFPL2, LHFPL tetraspan subfamily member 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LHFPL2, LHFPL tetraspan subfamily member 2
  • Links
    NCBI Gene ID: 10184
    neXtProt AC: NX_Q6ZUX7
    UniProt: Q6ZUX7

  • Chr Location
    5q14.1; chr5:78485215-78770021 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    22 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Females homozygous for a spontaneous point mutation have a completely closed vagina, soft swelling of the perineum and buildup of viscous fluid in the uteri.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    731
  • Tissues
    20
  • cDNA Data
    14
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000045312 Ensembl Gene Model | MGI Sequence Detail 137614 C57BL/6J ±  kb
    transcript ENSMUST00000118195 Ensembl | MGI Sequence Detail 3611 Not Applicable  
    polypeptide ENSMUSP00000112655 Ensembl | MGI Sequence Detail 222 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 15
      Primer pair 2

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:2145409, MGI:4837107
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 3
      Gene Ontology 4
      Phenotypes 14
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory