Asb13 Gene Detail

Summary

• Symbol
  Asb13
• Name
  ankyrin repeat and SOCS box-containing 13
• Synonyms
  2210015B19Rik, 6430573K02Rik

• Feature Type
  protein coding gene
• IDs
  MGI:2145525
  NCBI Gene: 142688
• Alliance
  gene page
• Transcription Start Sites
  3 TSS

Location &
Maps

• Sequence Map
  Chr13:3684032-3703822 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 13, 2.03 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  497 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2145525	protein coding gene	Chr13:3683589-3703822 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0020195	protein coding gene	Chr13:114327-145313 (+)
A/J	MGP_AJ_G0020151	protein coding gene	Chr13:225942-248856 (+)
AKR/J	MGP_AKRJ_G0020126	protein coding gene	Chr13:212466-230117 (+)
BALB/cJ	MGP_BALBcJ_G0020134	protein coding gene	Chr13:211024-235152 (+)
C3H/HeJ	MGP_C3HHeJ_G0019938	protein coding gene	Chr13:279457-298904 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0020581	protein coding gene	Chr13:182921-201569 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018193	protein coding gene	Chr13:166699-186615 (+)
CAST/EiJ	MGP_CASTEiJ_G0019478	protein coding gene	Chr13:130225-152020 (+)
CBA/J	MGP_CBAJ_G0019905	protein coding gene	Chr13:203514-221292 (+)
DBA/2J	MGP_DBA2J_G0020022	protein coding gene	Chr13:126908-147117 (+)
FVB/NJ	MGP_FVBNJ_G0020007	protein coding gene	Chr13:117960-136111 (+)
LP/J	MGP_LPJ_G0020096	protein coding gene	Chr13:180055-198414 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020043	protein coding gene	Chr13:212874-238268 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0020610	protein coding gene	Chr13:192839-213752 (+)
PWK/PhJ	MGP_PWKPhJ_G0019240	protein coding gene	Chr13:181521-206611 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0019045	protein coding gene	Chr13:236141-257535 (+)
WSB/EiJ	MGP_WSBEiJ_G0019536	protein coding gene	Chr13:119611-140962 (+)

Homology

• Human Ortholog
  ASB13, ankyrin repeat and SOCS box containing 13

• Vertebrate Orthologs
  5

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  ASB13, ankyrin repeat and SOCS box containing 13
  
• Links
  HGNC:19765

  NCBI Gene ID: 79754

  neXtProt AC: NX_Q8WXK3

  UniProt: Q8WXK3

  
  
• Chr Location
  10p15.1; chr10:5638867-5666595 (-)  GRCh38

---

• MGI Vertebrate Homology
  Asb13 stringent orthology
  1 human;1 mouse;1 rat;3 zebrafish
  
• HCOP
  vertebrate homology predictions: ASB13
• Gene Tree
  Asb13
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotype references
  

• All Mutations and Alleles
  6
• Endonuclease-mediated
  2
• Gene trapped
  2
• Targeted
  2
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  25 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  2
• GO References
  2

Expression

• Assay Results
  706
• cDNA Data
  32

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase asb13
  ZFIN asb13b

Sequences &
Gene Models

• All Sequences
  39
• RefSeq
  5
• UniProt
  1
• CCDS
  CCDS36582.1

• Ensembl
  ENSMUSG00000033781 (Evidence)
• NCBI Gene
  142688

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000033781	Ensembl Gene Model | MGI Sequence Detail	19791	C57BL/6J
transcript	ENSMUST00000042288	Ensembl | MGI Sequence Detail	4453	Not Applicable
polypeptide	ENSMUSP00000046476	Ensembl | MGI Sequence Detail	278	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000004345 ankyrin repeat and SOCS box protein 13
  (term hierarchy)
• InterPro Domains
  IPR002110 Ankyrin repeat
  IPR051573 Ankyrin repeat and SOCS box domain-containing protein
  IPR037334 Ankyrin repeat and SOCS box protein 13, SOCS box domain
  IPR036770 Ankyrin repeat-containing domain superfamily
  IPR001496 SOCS box domain
  IPR036036 SOCS box-like domain superfamily

Molecular
Reagents

• All nucleic 32

  cDNA 32

  
  

  Microarray probesets 5

Other
Accession IDs

MGI:1919596

References

• Summaries
  All 30

  Gene Ontology 2

  Phenotypes 5
• Earliest
  J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
• Latest
  J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

TSS for Asb13:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr118205	Chr13:3684012-3684027 (+)	-12 bp
Tssr118206	Chr13:3684034-3684108 (+)	39 bp
Tssr118207	Chr13:3702777-3702783 (+)	18,748 bp