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Ankrd28 Gene Detail
Summary
  • Symbol
    Ankrd28
  • Name
    ankyrin repeat domain 28
  • Synonyms
    E430019N21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145661
    NCBI Gene: 105522
  • Alliance
    gene page
  • Transcription Start Sites
    17 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:31420725-31552608 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 19.40 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2151 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2145661
 protein coding gene Chr14:31418687-31552608 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021134
 protein coding gene Chr14:24894924-25029742 (-)
A/J MGP_AJ_G0021082
 protein coding gene Chr14:23958943-24091304 (-)
AKR/J MGP_AKRJ_G0021059
 protein coding gene Chr14:25084393-25216001 (-)
BALB/cJ MGP_BALBcJ_G0021086
 protein coding gene Chr14:24094129-24228207 (-)
C3H/HeJ MGP_C3HHeJ_G0020869
 protein coding gene Chr14:24954603-25090960 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021518
 protein coding gene Chr14:25874754-26016466 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019081
 protein coding gene Chr14:24026978-24166055 (-)
CAST/EiJ MGP_CASTEiJ_G0020394
 protein coding gene Chr14:24750115-24890182 (-)
CBA/J MGP_CBAJ_G0020836
 protein coding gene Chr14:26852867-26986909 (-)
DBA/2J MGP_DBA2J_G0020958
 protein coding gene Chr14:23993496-24127468 (-)
FVB/NJ MGP_FVBNJ_G0020942
 protein coding gene Chr14:23947163-24079309 (-)
LP/J MGP_LPJ_G0021027
 protein coding gene Chr14:25219808-25354287 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020968
 protein coding gene Chr14:26111808-26256877 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021551
 protein coding gene Chr14:24852107-24991007 (-)
PWK/PhJ MGP_PWKPhJ_G0020142
 protein coding gene Chr14:23458684-23596872 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019966
 protein coding gene Chr14:24466443-24607044 (-)
WSB/EiJ MGP_WSBEiJ_G0020449
 protein coding gene Chr14:24926569-25062990 (-)



Homology
more
  • Human Ortholog
    ANKRD28, ankyrin repeat domain 28
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANKRD28, ankyrin repeat domain 28
  • Synonyms
    CFAP79, FAP79, PITK, PPP1R65
  • Links
    NCBI Gene ID: 23243
    neXtProt AC: NX_O15084
    UniProt: O15084

  • Chr Location
    3p25.1; chr3:15667236-15859814 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    14
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000014496 Ensembl Gene Model | MGI Sequence Detail 131884 C57BL/6J ±  kb
    transcript ENSMUST00000227863 Ensembl | MGI Sequence Detail 6616 Not Applicable  
    polypeptide ENSMUSP00000153992 Ensembl | MGI Sequence Detail 1083 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      6 Sequences
    • Protein Ontology
      PR:000004047 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
      (term hierarchy)
    • InterPro Domains
      IPR002110 Ankyrin repeat
      IPR050776 Ankyrin Repeat and Cyclin-Dependent Kinase Inhibitor
      IPR036770 Ankyrin repeat-containing domain superfamily
      IPR050842 Cul2-RING E3 Ligase Substrate-Recognition Fem-1
      IPR050889 Dendritic Spine Regulation and Scaffold
      IPR050745 Multifunctional regulatory proteins
    • GlyGen
      Q505D1 2 sites, 1 O-linked glycan (2 sites)
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 15

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:2145679
    References
    more
    • Summaries
      All 30
      Gene Ontology 1
      Phenotypes 6
    • Earliest
      J:34960 Chambers DM, et al., Isolation and mapping of novel mouse brain cDNA clones containing trinucleotide repeats, and demonstration of novel alleles in recombinant inbred strains. Genome Res. 1996 Aug;6(8):715-23
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory