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Slc38a1 Gene Detail
Summary
  • Symbol
    Slc38a1
  • Name
    solute carrier family 38, member 1
  • Synonyms
    NAT2, SNAT1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145895
    NCBI Gene: 105727
  • Alliance
    gene page
  • Transcription Start Sites
    26 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:96469299-96540794 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 52.53 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2177 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2145895
 protein coding gene Chr15:96469299-96541396 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022270
 protein coding gene Chr15:98162540-98233236 (-)
A/J MGP_AJ_G0022229
 protein coding gene Chr15:94315544-94388456 (-)
AKR/J MGP_AKRJ_G0022204
 protein coding gene Chr15:97148994-97232781 (-)
BALB/cJ MGP_BALBcJ_G0022235
 protein coding gene Chr15:94522166-94595852 (-)
C3H/HeJ MGP_C3HHeJ_G0022005
 protein coding gene Chr15:97201176-97272500 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022680
 protein coding gene Chr15:101793165-101866867 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020206
 protein coding gene Chr15:90307483-90379255 (-)
CAST/EiJ MGP_CASTEiJ_G0021527
 protein coding gene Chr15:98074464-98149276 (-)
CBA/J MGP_CBAJ_G0021972
 protein coding gene Chr15:105183405-105265063 (-)
DBA/2J MGP_DBA2J_G0022099
 protein coding gene Chr15:93757970-93827785 (-)
FVB/NJ MGP_FVBNJ_G0022078
 protein coding gene Chr15:92756160-92825815 (-)
LP/J MGP_LPJ_G0022170
 protein coding gene Chr15:98279878-98356752 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022098
 protein coding gene Chr15:109388537-109474118 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022695
 protein coding gene Chr15:97277173-97353276 (-)
PWK/PhJ MGP_PWKPhJ_G0021268
 protein coding gene Chr15:93837894-93912543 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021102
 protein coding gene Chr15:97084939-97158360 (-)
WSB/EiJ MGP_WSBEiJ_G0021576
 protein coding gene Chr15:97797066-97871904 (-)



Homology
more
  • Human Ortholog
    SLC38A1, solute carrier family 38 member 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC38A1, solute carrier family 38 member 1
  • Synonyms
    ATA1, NAT2, SAT1, SNAT1
  • Links
    NCBI Gene ID: 81539
    neXtProt AC: NX_Q9H2H9
    UniProt: Q9H2H9

  • Chr Location
    12q13.11; chr12:46183063-46270017 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SLC38A1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    37 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    44
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1085
  • Tissues
    84
  • cDNA Data
    24
  • Literature Summary
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023169 Ensembl Gene Model | MGI Sequence Detail 71496 C57BL/6J ±  kb
transcript ENSMUST00000088452 Ensembl | MGI Sequence Detail 7266 Not Applicable  
polypeptide ENSMUSP00000085799 Ensembl | MGI Sequence Detail 485 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 27
    cDNA 24
    Primer pair 3

    Microarray probesets 4
Other
Accession IDs
less
MGI:2145903, MGI:2146107, MGI:2146126
References
more
  • Summaries
    All 80
    Developmental Gene Expression 9
    Diseases 1
    Gene Ontology 11
    Phenotypes 37
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:331835 Salazar-Petres E, et al., Placental structure, function, and mitochondrial phenotype relate to fetal size in each fetal sex in mice. Biol Reprod. 2022 Jun 13;106(6):1292-1311
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory