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Shisa8 Gene Detail
Summary
  • Symbol
    Shisa8
  • Name
    shisa family member 8
  • Synonyms
    AI848285, CKAMP39, Orf26
  • Feature Type
    protein coding gene
  • IDs
    MGI:2146080
    NCBI Gene: 435145
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:82091153-82097004 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, Syntenic
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    172 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2146080
 protein coding gene Chr15:82090369-82097016 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022136
 protein coding gene Chr15:82702910-82710046 (-)
A/J MGP_AJ_G0022096
 protein coding gene Chr15:79774185-79780105 (-)
AKR/J MGP_AKRJ_G0022072
 protein coding gene Chr15:81983014-81988856 (-)
BALB/cJ MGP_BALBcJ_G0022102
 protein coding gene Chr15:79824226-79830068 (-)
C3H/HeJ MGP_C3HHeJ_G0021873
 protein coding gene Chr15:82002782-82008624 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022545
 protein coding gene Chr15:85939433-85945377 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020074
 protein coding gene Chr15:76215032-76220625 (-)
CAST/EiJ MGP_CASTEiJ_G0021393
 protein coding gene Chr15:82798395-82805112 (-)
CBA/J MGP_CBAJ_G0021838
 protein coding gene Chr15:88627144-88633016 (-)
DBA/2J MGP_DBA2J_G0021966
 protein coding gene Chr15:79247569-79253412 (-)
FVB/NJ MGP_FVBNJ_G0021943
 protein coding gene Chr15:78307446-78313706 (-)
LP/J MGP_LPJ_G0022035
 protein coding gene Chr15:82845992-82852965 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021964
 protein coding gene Chr15:93537742-93543584 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022559
 protein coding gene Chr15:82096643-82103830 (-)
PWK/PhJ MGP_PWKPhJ_G0021135
 protein coding gene Chr15:79301260-79307585 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020974
 protein coding gene Chr15:81877199-81884938 (-)
WSB/EiJ MGP_WSBEiJ_G0021444
 protein coding gene Chr15:82511165-82516992 (-)



Homology
more
  • Human Ortholog
    SHISA8, shisa family member 8
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SHISA8, shisa family member 8
  • Synonyms
    C22orf17, Orf26
  • Links
    NCBI Gene ID: 440829
    neXtProt AC: NX_B8ZZ34
    UniProt: B8ZZ34

  • Chr Location
    22q13.2; chr22:41909543-41915074 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    22 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Radiation induced
    2
  • Genomic Mutations
    3 involving Shisa8
  • Find Mice (IMSR)
    8 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    725
  • Tissues
    5
  • cDNA Data
    12
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 435145 NCBI Gene Model | MGI Sequence Detail 5852 C57BL/6J ±  kb
transcript NM_001415947 RefSeq | MGI Sequence Detail 1838 ZRU/MplStud  
polypeptide J3QNX5 UniProt | EBI | MGI Sequence Detail 399 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 12
    Primer pair 1
    Other 1

    Microarray probesets 1
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 2
    Phenotypes 22
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory