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Slc25a45 Gene Detail
Summary
  • Symbol
    Slc25a45
  • Name
    solute carrier family 25, member 45
  • Feature Type
    protein coding gene
  • IDs
    MGI:2147731
    NCBI Gene: 107375
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:5927828-5935796 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 19, 4.34 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    308 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2147731
protein coding gene Chr19:5927828-5935906 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024730
protein coding gene Chr19:2882671-2890626 (+)
A/J MGP_AJ_G0024696
protein coding gene Chr19:2720924-2729579 (+)
AKR/J MGP_AKRJ_G0024669
protein coding gene Chr19:2801414-2813115 (+)
BALB/cJ MGP_BALBcJ_G0024696
protein coding gene Chr19:2713350-2721299 (+)
C3H/HeJ MGP_C3HHeJ_G0024464
protein coding gene Chr19:2812528-2822155 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025143
protein coding gene Chr19:2943149-2951098 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022573
protein coding gene Chr19:2630720-2638048 (+)
CAST/EiJ MGP_CASTEiJ_G0023936
protein coding gene Chr19:2828162-2836127 (+)
CBA/J MGP_CBAJ_G0024436
protein coding gene Chr19:3086137-3094086 (+)
DBA/2J MGP_DBA2J_G0024563
protein coding gene Chr19:2713358-2721307 (+)
FVB/NJ MGP_FVBNJ_G0024529
protein coding gene Chr19:2717723-2725727 (+)
LP/J MGP_LPJ_G0024649
protein coding gene Chr19:2843245-2851200 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024559
protein coding gene Chr19:2911975-2919930 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025191
protein coding gene Chr19:2820319-2828274 (+)
PWK/PhJ MGP_PWKPhJ_G0023682
protein coding gene Chr19:2741115-2749205 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023487
protein coding gene Chr19:2806878-2814886 (+)
WSB/EiJ MGP_WSBEiJ_G0023998
protein coding gene Chr19:2827855-2835805 (+)



Homology
more
  • Human Ortholog
    SLC25A45, solute carrier family 25 member 45
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC25A45, solute carrier family 25 member 45
  • Links
    NCBI Gene ID: 283130
    neXtProt AC: NX_Q8N413
    UniProt: Q8N413

  • Chr Location
    11q13.1; chr11:65375192-65383701 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 107375 NCBI Gene Model | MGI Sequence Detail 7969 C57BL/6J ±  kb
transcript NM_001425851 RefSeq | MGI Sequence Detail 2540 C57BL/6  
polypeptide Q8CFJ7 UniProt | EBI | MGI Sequence Detail 288 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 39
    cDNA 38
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory