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Acaa1a Gene Detail
Summary
  • Symbol
    Acaa1a
  • Name
    acetyl-Coenzyme A acyltransferase 1A
  • Synonyms
    Acaa1, D9Ertd25e, MGC:7090, peroxisomal 3-ketoacyl-CoA thiolase, PTL, thiolase A
  • Feature Type
    protein coding gene
  • IDs
    MGI:2148491
    NCBI Gene: 113868
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:119170113-119179361 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 71.33 cM, cytoband F4
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    330 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2148491
 protein coding gene Chr9:119168742-119179365 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035417
 protein coding gene Chr9:122101825-122115474 (+)
A/J MGP_AJ_G0035398
 protein coding gene Chr9:117559218-117570288 (+)
AKR/J MGP_AKRJ_G0035331
 protein coding gene Chr9:120627352-120638547 (+)
BALB/cJ MGP_BALBcJ_G0035394
 protein coding gene Chr9:117436033-117445690 (+)
C3H/HeJ MGP_C3HHeJ_G0035102
 protein coding gene Chr9:121090134-121102834 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035917
 protein coding gene Chr9:125438873-125452513 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032799
 protein coding gene Chr9:114758228-114768818 (+)
CAST/EiJ MGP_CASTEiJ_G0034405
 protein coding gene Chr9:121067624-121079261 (+)
CBA/J MGP_CBAJ_G0035069
 protein coding gene Chr9:130146834-130156571 (+)
DBA/2J MGP_DBA2J_G0035228
 protein coding gene Chr9:117001882-117014013 (+)
FVB/NJ MGP_FVBNJ_G0035175
 protein coding gene Chr9:115853095-115867673 (+)
LP/J MGP_LPJ_G0035307
 protein coding gene Chr9:122451189-122461609 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035216
 protein coding gene Chr9:131120928-131131237 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035936
 protein coding gene Chr9:121006921-121020044 (+)
PWK/PhJ MGP_PWKPhJ_G0034111
 protein coding gene Chr9:117425790-117437916 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033947
 protein coding gene Chr9:121113431-121125861 (+)
WSB/EiJ MGP_WSBEiJ_G0034526
 protein coding gene Chr9:120895793-120907158 (+)



Homology
more
  • Human Ortholog
    ACAA1, acetyl-CoA acyltransferase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACAA1, acetyl-CoA acyltransferase 1
  • Synonyms
    ACAA, Lnc-Myd88, PTHIO, THIO
  • Links
    NCBI Gene ID: 30
    neXtProt AC: NX_P09110
    UniProt: P09110

  • Chr Location
    3p22.2; chr3:38103129-38137242 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    29
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    966
  • Tissues
    121
  • cDNA Data
    186
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 113868 NCBI Gene Model | MGI Sequence Detail 9249 C57BL/6J ±  kb
transcript NM_001421420 RefSeq | MGI Sequence Detail 1778 ZRU/MplStud  
polypeptide Q921H8 UniProt | EBI | MGI Sequence Detail 424 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 191
    cDNA 188
    Primer pair 2
    Other 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:1098606
References
more
  • Summaries
    All 47
    Developmental Gene Expression 7
    Gene Ontology 8
    Phenotypes 8
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory