About   Help   FAQ
Krt23 Gene Detail
Summary
  • Symbol
    Krt23
  • Name
    keratin 23
  • Synonyms
    CK23, K23, Krt1-23
  • Feature Type
    protein coding gene
  • IDs
    MGI:2148866
    NCBI Gene: 94179
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:99368799-99383946 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 62.92 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    635 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2148866
 protein coding gene Chr11:99368799-99383963 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019094
 protein coding gene Chr11:102146462-102161625 (-)
A/J MGP_AJ_G0019062
 protein coding gene Chr11:97846459-97861534 (-)
AKR/J MGP_AKRJ_G0019032
 protein coding gene Chr11:100886914-100902037 (-)
BALB/cJ MGP_BALBcJ_G0019036
 protein coding gene Chr11:98357485-98372578 (-)
C3H/HeJ MGP_C3HHeJ_G0018849
 protein coding gene Chr11:101032648-101047777 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019486
 protein coding gene Chr11:105280842-105295969 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017119
 protein coding gene Chr11:95407709-95423028 (-)
CAST/EiJ MGP_CASTEiJ_G0018404
 protein coding gene Chr11:102030876-102045955 (-)
CBA/J MGP_CBAJ_G0018820
 protein coding gene Chr11:109673361-109688474 (-)
DBA/2J MGP_DBA2J_G0018928
 protein coding gene Chr11:97412087-97427200 (-)
FVB/NJ MGP_FVBNJ_G0018917
 protein coding gene Chr11:96923255-96938384 (-)
LP/J MGP_LPJ_G0018998
 protein coding gene Chr11:102613116-102628213 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018944
 protein coding gene Chr11:109338299-109353408 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019527
 protein coding gene Chr11:101249157-101264242 (-)
PWK/PhJ MGP_PWKPhJ_G0018175
 protein coding gene Chr11:98488294-98503391 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017963
 protein coding gene Chr11:100991241-101006313 (-)
WSB/EiJ MGP_WSBEiJ_G0018452
 protein coding gene Chr11:101215299-101230400 (-)



Homology
more
  • Human Ortholog
    KRT23, keratin 23
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRT23, keratin 23
  • Synonyms
    CK23, HAIK1, K23
  • Links
    NCBI Gene ID: 25984
    neXtProt AC: NX_Q9C075
    UniProt: Q9C075

  • Chr Location
    17q21.2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    866
  • Tissues
    60
  • cDNA Data
    26
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 94179 NCBI Gene Model | MGI Sequence Detail 15148 C57BL/6J ±  kb
    transcript NM_033373 RefSeq | MGI Sequence Detail 1570 C57BL/6  
    polypeptide Q99PS0 UniProt | EBI | MGI Sequence Detail 422 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 28
      cDNA 26
      Primer pair 1
      Other 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 6
      Gene Ontology 3
      Phenotypes 13
    • Earliest
      J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory