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Obox3 Gene Detail
Summary
  • Symbol
    Obox3
  • Name
    oocyte specific homeobox 3
  • Synonyms
    Ohx
  • Feature Type
    protein coding gene
  • IDs
    MGI:2149032
    NCBI Gene: 246791
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr7:15359231-15373702 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 8.53 cM, cytoband A3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    201 from dbSNP Build 142
  • Strain Annotations
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2149032
 protein coding gene Chr7:15359227-15373827 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J MGP_AKRJ_G0031586
 protein coding gene Chr7:12326061-12327273 (+)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0032130
 protein coding gene Chr7:12797841-14101771 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0031461
 protein coding gene Chr7:11846509-11847721 (+)
LP/J MGP_LPJ_G0031590
 protein coding gene Chr7:12344231-12345443 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0022460
 protein coding gene Chr17:34500798-34501822 (-)
WSB/EiJ MGP_WSBEiJ_G0030838
 protein coding gene Chr7:13308284-13309496 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    782
  • Tissues
    33
  • cDNA Data
    6
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 246791 NCBI Gene Model | MGI Sequence Detail 14472 C57BL/6J ±  kb
transcript NM_145707 RefSeq | MGI Sequence Detail 1603 C57BL/6  
polypeptide Q3UT54 UniProt | EBI | MGI Sequence Detail 335 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR050460 Distal-less homeobox transcription factors
    IPR017970 Homeobox, conserved site
    IPR001356 Homeobox domain
    IPR009057 Homeobox-like domain superfamily
Molecular
Reagents
less
  • All nucleic 11
    cDNA 7
    Primer pair 3
    Other 1

    Microarray probesets 4
References
more
  • Summaries
    All 25
    Developmental Gene Expression 6
    Gene Ontology 4
    Phenotypes 1
  • Earliest
    J:76506 Rajkovic A, et al., Obox, a family of homeobox genes preferentially expressed in germ cells. Genomics. 2002 May;79(5):711-7
  • Latest
    J:340071 Ji S, et al., OBOX regulates mouse zygotic genome activation and early development. Nature. 2023 Aug;620(7976):1047-1053
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory