About   Help   FAQ
Ugt2a1 Gene Detail
Summary
  • Symbol
    Ugt2a1
  • Name
    UDP glucuronosyltransferase 2 family, polypeptide A1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2149905
    NCBI Gene: 94215
  • Member of
    Ugt2 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:87607349-87638730 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 43.56 cM, cytoband E2
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1158 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2149905
 protein coding gene Chr5:87607349-87638730 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029683
 protein coding gene Chr5:88382889-88415795 (-)
A/J MGP_AJ_G0029650
 protein coding gene Chr5:84778155-84818302 (-)
AKR/J MGP_AKRJ_G0029596
 protein coding gene Chr5:87587672-87628816 (-)
BALB/cJ MGP_BALBcJ_G0029659
 protein coding gene Chr5:85677854-85710953 (-)
C3H/HeJ MGP_C3HHeJ_G0029382
 protein coding gene Chr5:88015659-88047714 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030113
 protein coding gene Chr5:91823144-92057009 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027352
 protein coding gene Chr5:80426747-80459050 (-)
CAST/EiJ MGP_CASTEiJ_G0028792
 protein coding gene Chr5:87365089-87399806 (-)
CBA/J MGP_CBAJ_G0029351
 protein coding gene Chr5:94914386-94953077 (-)
DBA/2J MGP_DBA2J_G0029496
 protein coding gene Chr5:84966870-84999482 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0029584
 protein coding gene Chr5:88797318-88836327 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029486
 protein coding gene Chr5:99888347-99929715 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030147
 protein coding gene Chr5:87149054-87186283 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0028349
 protein coding gene Chr5:86608535-86663299 (-)
WSB/EiJ MGP_WSBEiJ_G0028871
 protein coding gene Chr5:87532919-87572469 (-)



Homology
more
  • Human Ortholog
    UGT2A1, UDP glucuronosyltransferase family 2 member A1 complex locus
  • Vertebrate Orthologs
    7
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UGT2A1, UDP glucuronosyltransferase family 2 member A1 complex locus
  • Synonyms
    UDPGT2A1
  • Links
    NCBI Gene ID: 10941
    neXtProt AC: NX_P0DTE4
    UniProt: P0DTE4

  • Chr Location
    4q13.3; chr4:69588417-69653249 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    810
  • Tissues
    95
  • cDNA Data
    5
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 94215 NCBI Gene Model | MGI Sequence Detail 31382 C57BL/6J ±  kb
transcript NM_053184 RefSeq | MGI Sequence Detail 2597 C57BL/6  
polypeptide Q80X89 UniProt | EBI | MGI Sequence Detail 528 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • EC
    2.4.1.17
  • InterPro Domains
    IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase
    IPR050271 UDP-glycosyltransferase
    IPR035595 UDP-glycosyltransferase family, conserved site
  • GlyGen
    Q80X89 2 sites
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 31
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory