Lch Gene Detail

Summary

• Symbol
  Lch
• Name
  low cholesterol
• Synonyms
  Gena241, low HDL cholesterol

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:2152768
  NCBI Gene: 117562
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr4:45658442-67100408 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 4, Syntenic
• Mapping Data
  2 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from 1 allele in 1 genetic background
  5 phenotype references
  

• All Mutations and Alleles
  1
• Chemically induced (ENU)
  1
• Find Mice (IMSR)
  2 strains or lines available

Mice heterozygous for this ENU-induced mutation exhibit decreased circulating total and HDL cholesterol levels.

Sequences &
Gene Models

• NCBI Gene
  117562

Other
Accession IDs

MGI:3686751

References

• Summaries
  All 7

  Phenotypes 5
• Earliest
  J:79719 Hough TA, et al., Novel phenotypes identified by plasma biochemical screening in the mouse. Mamm Genome. 2002 Oct;13(10):595-602
• Latest
  J:88732 Lyons MA, et al., Quantitative trait loci that determine lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and CAST/Ei inbred mice. Physiol Genomics. 2004 Mar 12;17(1):60-8